Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Osteoblast expression of an engineered Gs-coupled receptor dramatically increases bone mass. 2008 Proc Natl Acad Sci U S A
Polysialic acid, a glycan with highly restricted expression, is found on human and murine leukocytes and modulates immune responses. 2008 J Immunol
Probing for mitochondrial complex activity in human embryonic stem cells. 2008 J Vis Exp
Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation. 2008 Cell Stem Cell
Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium. 2008 Proc Natl Acad Sci U S A
Regulated beta-cell regeneration in the adult mouse pancreas. 2008 Diabetes
Regulation of Abeta pathology by beclin 1: a protective role for autophagy? 2008 J Clin Invest
Regulation of self-renewal and pluripotency by Sox2 in human embryonic stem cells. 2008 Stem Cells
Regulatory networks define phenotypic classes of human stem cell lines. 2008 Nature
Regulatory Priorities Governing Stem Cell Research in California: Relaxing Revenue Sharing & Safeguarding Access Plans 2008 Berkeley Technology Law Journal
Retinoic acid synthesis and signaling during early organogenesis. 2008 Cell
Role of gap junctions in embryonic and somatic stem cells. 2008 Stem Cell Rev
Roles of ESCRT in autophagy-associated neurodegeneration. 2008 Autophagy
SATB1 reprogrammes gene expression to promote breast tumour growth and metastasis. 2008 Nature
Selective inhibition of JAK2-driven erythroid differentiation of polycythemia vera progenitors. 2008 Cancer Cell
Shrinky-dink hanging drops: a simple way to form and culture embryoid bodies. 2008 J Vis Exp
Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates. 2008 Cancer Cell
Stabilization of beta-catenin induces pancreas tumor formation. 2008 Gastroenterology
Stem/progenitor cells in lung development, injury repair, and regeneration. 2008 Proc Am Thorac Soc
The 5th International Society for Stem Cell Research (ISSCR) Annual Meeting, June 2007. 2008 Stem Cells
The Fezf2-Ctip2 genetic pathway regulates the fate choice of subcortical projection neurons in the developing cerebral cortex. 2008 Proc Natl Acad Sci U S A
The N-end rule pathway is a sensor of heme. 2008 Proc Natl Acad Sci U S A
The pluripotent transcriptome 2008 Stembook
Tissue-specific expression of Cre recombinase from the Tgfb3 locus. 2008 Genesis
Transcription factor MEF2C influences neural stem/progenitor cell differentiation and maturation in vivo. 2008 Proc Natl Acad Sci U S A
Transcriptional and functional profiling of human embryonic stem cell-derived cardiomyocytes. 2008 PLoS One
Transforming growth factor-beta activation promotes genetic context-dependent invasion of immortalized melanocytes. 2008 Cancer Res
Use of bioluminescent imaging to assay the transplantation of immortalized human fetal hepatocytes into mice. 2008 Cell Transplant
Wnt signaling mediates self-organization and axis formation in embryoid bodies. 2008 Cell Stem Cell
Wnt-mediated self-renewal of neural stem/progenitor cells. 2008 Proc Natl Acad Sci U S A
Wnt/beta-catenin signaling acts at multiple developmental stages to promote mammalian cardiogenesis. 2008 Cell Cycle
X-inactivation in female human embryonic stem cells is in a nonrandom pattern and prone to epigenetic alterations. 2008 Proc Natl Acad Sci U S A
A chemical approach to stem cell biology. 2007 Curr Opin Chem Biol
A conserved phosphatase cascade that regulates nuclear membrane biogenesis. 2007 Proc Natl Acad Sci U S A
A developmental view of microRNA function. 2007 Trends Biochem Sci
A gene regulatory network subcircuit drives a dynamic pattern of gene expression. 2007 Science
A global analysis of genetic interactions in Caenorhabditis elegans. 2007 J Biol
A phenotypic small-molecule screen identifies an orphan ligand-receptor pair that regulates neural stem cell differentiation. 2007 Chem Biol
Age-related defects in B lymphopoiesis underlie the myeloid dominance of adult leukemia. 2007 Blood
Aging, B lymphopoiesis, and patterns of leukemogenesis. 2007 Exp Gerontol
Alternative splicing events identified in human embryonic stem cells and neural progenitors. 2007 PLoS Comput Biol
An optical neural interface: in vivo control of rodent motor cortex with integrated fiberoptic and optogenetic technology. 2007 J Neural Eng
Ancient evolutionary origin of the neural crest gene regulatory network. 2007 Dev Cell
Antithrombogenic property of bone marrow mesenchymal stem cells in nanofibrous vascular grafts. 2007 Proc Natl Acad Sci U S A
Bioelectricity and epimorphic regeneration. 2007 Bioessays
Cancer stem cells and tumor metastasis: first steps into uncharted territory. 2007 Cell Stem Cell
Cancer stem cells: models and concepts. 2007 Annu Rev Med
Conservation of hearing by simultaneous mutation of Na,K-ATPase and NKCC1. 2007 J Assoc Res Otolaryngol
Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. 2007 Nature
Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality. 2007 Mol Cell Biol