In neurons and beyond: how protein interactions shape the cellular response to Huntington’s Disease

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Grant Award Details

Grant Number:
DISC0-17566
Investigator(s):
Award Value:
$2,056,195
Status:
Pre-Active

Grant Application Details

Application Title:

In neurons and beyond: how protein interactions shape the cellular response to Huntington's Disease

Public Abstract:
Research Objective

New knowledge relating to protein-protein interactions that drive vulnerability of different cell types to neurodegeneration disease mutations using Huntington's disease as a paradigm.

Impact

The studies will inform current gaps in knowledge about drivers of cell-type specific functions of Huntington and cell vulnerability in Huntington’s disease and other neurodegenerative diseases.