TY1 and Semaglutide to Treat Cardiometabolic HFpEF

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CRISPR/Cas9-mediated gene editing of Hematopoietic stem and progenitor cells for Friedreich’s ataxia

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Noncoding RNA drug TY2 for arrhythmogenic cardiomyopathy

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Development of an AAV Epigenetic Gene Therapy for Intractable Chronic Pain Disorders

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Stem Cell-Based Cartilage Tissue Regeneration

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Autologous iPSC-derived progenitor smooth muscle cells for treatment of urinary incontinence

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Transplantation of human forebrain assembloids as a platform for therapeutic screening in neurodevelopmental disorders

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Advancing Therapeutic Discovery Through Multimodal Analyses of Genetic and Cellular Mechanisms in Neuropsychiatric Disorders

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Translational epigenomics: dissecting cell type-specific function of neuropsychiatric risk genes in vivo

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Research Objective Our objective is to enable scalable genetic screening to study how different cell types and epigenetic networks are impacted by risk genes implicated in human psychiatric disorders. Impact…

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Identifying and Overcoming Roadblocks to Hearing Restoration Using Human Induced Pluripotent Stem Cells

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Research Objective To utilize human iPSCs as an in vitro model of hearing loss and overcome obstacles to hair cell regeneration by prompting post-mitotic supporting cells to re-enter the cell…

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