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Stem Cell-Mediated Oncocidal Gene Therapy of Glioblastoma (GBM)

  • Post author:
  • Post published:May 24, 2025
  • Post category:

Brain tumors (BTs) are incurable, whether they start in the brain or spread there from other sites. Despite advances in surgical, radiation, pharmacologic, and gene therapies, survival with a BT…

Continue ReadingStem Cell-Mediated Oncocidal Gene Therapy of Glioblastoma (GBM)

Stem Cell-mediated Therapy for High-grade Glioma: Toward Phase I-II Clinical Trials

  • Post author:
  • Post published:May 24, 2025
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Despite aggressive multimodal therapy and advances in imaging, surgical and radiation techniques, malignant brain tumors (high-grade gliomas) remain incurable, with survival often measured in months. Treatment failure is largely attributable…

Continue ReadingStem Cell-mediated Therapy for High-grade Glioma: Toward Phase I-II Clinical Trials

iPS Cell-Based Treatment of Dominant Dystrophic Epidermolysis Bullosa

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  • Post published:May 24, 2025
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Genetic skin diseases constitute a diverse group of several hundred diseases that affect up to 2% of the population and include common disease such as psoriasis, atopic dermatitis, and wound…

Continue ReadingiPS Cell-Based Treatment of Dominant Dystrophic Epidermolysis Bullosa

ZINC FINGER NUCLEASE-BASED STEM CELL THERAPY FOR AIDS

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  • Post published:May 24, 2025
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Some years ago it was discovered that patients homozygous for a natural mutation (the Δ32 mutation) in the CCR5 gene are generally resistant to HIV infection by blocking virus entry…

Continue ReadingZINC FINGER NUCLEASE-BASED STEM CELL THERAPY FOR AIDS

Evaluation of Gene Therapy Approaches for Autosomal Recessive Hyper IgE Syndrome Due to Mutations in DOCK8

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  • Post published:September 12, 2024
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Continue ReadingEvaluation of Gene Therapy Approaches for Autosomal Recessive Hyper IgE Syndrome Due to Mutations in DOCK8
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