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Identifying sources of mutation in human induced pluripotent stem cells by whole genome sequencing

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  • Post published:December 26, 2025
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Stem cell research offers new tools to help treat and cure diseases that affect diverse cells types in the body such as neurological diseases, heart disease and diabetes by producing…

Continue ReadingIdentifying sources of mutation in human induced pluripotent stem cells by whole genome sequencing

Ubiquitin-dependent control of hESC self-renewal and expansion

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  • Post published:December 26, 2025
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Human embryonic stem cells (hESCs) or induced pluripotent stem cells (iPSCs) provide an invaluable resource for regenerative medicine and disease modeling. To be able to use these cells in the…

Continue ReadingUbiquitin-dependent control of hESC self-renewal and expansion

Forming the Hematopoietic Niche from Human Pluripotent Stem Cells

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  • Post published:December 26, 2025
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The clinical potential of pluripotent stem cells for use in regenerative medicine will be realized only when the process by which tissues are generated from these cells is significantly more…

Continue ReadingForming the Hematopoietic Niche from Human Pluripotent Stem Cells

Biological relevance of microRNAs in hESC differentiation to endocrine pancreas

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  • Post published:December 26, 2025
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There remains an urgent and critical need for a cell-based cure of diabetes, one of the most costly diseases in California. Islet transplantation with persistent immune suppression has shown promise…

Continue ReadingBiological relevance of microRNAs in hESC differentiation to endocrine pancreas

Induced Pluripotent Stem Cells for Tissue Regeneration

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  • Post published:December 26, 2025
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Induced pluripotent stem cells (iPSCs) have tremendous potential for patient-specific cell therapies, which bypasses immune rejection issues and ethical concerns for embryonic stem cells (ESCs). However, to fully harness the…

Continue ReadingInduced Pluripotent Stem Cells for Tissue Regeneration

Niche-Focused Research: Discovery & Development of Hematopoietic Regenerative Factors

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  • Post published:December 26, 2025
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Bone marrow and peripheral blood transplantation utilizing blood stem cells can provide curative treatment for patients with cancers and non-cancerous diseases of the blood and immune systems. Such treatments can…

Continue ReadingNiche-Focused Research: Discovery & Development of Hematopoietic Regenerative Factors

Epithelial progenitors and the stromal niche as therapeutic targets in lung disease

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  • Post published:December 26, 2025
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Chronic lung disease is an enormous societal and medical problem in California and the nation as a whole, representing the third most likely cause of death. Treatment costs were $389.2…

Continue ReadingEpithelial progenitors and the stromal niche as therapeutic targets in lung disease

Repair and regeneration of the nephron

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  • Post published:December 26, 2025
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Kidney function is essential for removing the wastes that result from normal cell function and maintaining water and salt balance in our internal tissues. These actions are carried out by…

Continue ReadingRepair and regeneration of the nephron

The role of neural stem cells in cerebellar development, regeneration and tumorigenesis

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  • Post published:December 26, 2025
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Stem cells have the remarkable ability to renew themselves and to generate multiple different cell types. This allows them to generate normal tissues during development and to repair tissues following…

Continue ReadingThe role of neural stem cells in cerebellar development, regeneration and tumorigenesis

Medical School Loan Repayment Program

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  • Post published:December 26, 2025
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Congenital and acquired defects of cardiac pacemakers are leading causes of morbidity and mortality in our society. Dysfunctions of the SA node and the lower conduction cells lead to a…

Continue ReadingMedical School Loan Repayment Program
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