Basic Biology

One perplexing question in regenerative medicine is why the human heart muscle cells are unable to divide and multiply their numbers. If they could, maybe they'd be able to produce new heart cells to replace those lost after a heart attack. Newts and salamanders can do it, why can't we?

A new Nature paper from CIRM grantees at Stanford University once again shows the value of reprogrammed iPS cells in understanding disease. Scientists can't develop a therapy for a disease if they don't know what it is going wrong. In many cases, iPS cells have provided the first ever way of peering into diseased cells and finding which proteins and genes need fixing.