Micro Platform for Controlled Cardiac Myocyte Differentiation
Congestive heart failure, the inability of the heart to continue to pump effectively due to damage of its muscle cells, affects approximately 4.8 million Americans and is a leading cause…
Micro Platform for Controlled Cardiac Myocyte Differentiation
Congestive heart failure, the inability of the heart to continue to pump effectively due to damage of its muscle cells, affects approximately 4.8 million Americans and is a leading cause…
CIRM Center for Neuropsychiatric Stem Cell Proteomics
Research Objective This project will interrogate interactions, distribution, and function of high-confidence neuropsychiatric disorder risk proteins, and identify convergent pathobiology of patient genetic variants. Impact Datasets and stem cell resources…
A Center for Stem Cell Disease Modeling and Therapeutics
The goal of this project is to support the discovery and evaluation of novel therapeutics using stem cell-based models and drug and CRISPR screening. The facility will provide California researchers…
CIRM ASCEND Center – Advancing Stem Cell Education and Novel Discoveries
The proposed CIRM ASCEND Center provides cutting-edge organoid-based services, offering consultation, optimized protocols, and genomic analysis. We also offer comprehensive training, workshops, and access to data, empowering researchers across California…
A modular automation approach to stem cell modeling to increase throughput, reproducibility and access
This project enhances stem cell access, scalability, and collaboration. It offers characterized hPSC lines, CRISPR editing, and differentiation on automated platforms accelerating progress in biology, disease research, and regenerative medicine.…
Shared Resources Laboratories to Enhance In Vitro Stem Cell Modeling and Training
Our broad objective is to expand access to equipment, services, and training within our areas of excellence. Through knowledge sharing and collaboration, we aim to add value to the CIRM…
Stem Cell-based Disease Modeling Shared Resource Laboratory
Our Shared Resource Laboratory will expand access to stem cell-derived models to support research and educational programs with two main goals: democratize access to state-of-the-art models and technology among a…
Creating A Collaborative California Cell and Gene Therapy Manufacturing Network
The need for cell and gene therapy product manufacturing will be ever increasing over the next decade, and several new GMP facilities are coming online. We believe it is important…
Scalable Expansion for Stem Cell-derived Therapies
Succesful completion of this proposal will identify a scalable process that supports iPSC expansion, T cell expansion, and cardiomyocyte maturation / expansion that is ready for validation in a large…
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