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  • About
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Identifying sources of mutation in human induced pluripotent stem cells by whole genome sequencing

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  • Post published:May 9, 2025
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Stem cell research offers new tools to help treat and cure diseases that affect diverse cells types in the body such as neurological diseases, heart disease and diabetes by producing…

Continue ReadingIdentifying sources of mutation in human induced pluripotent stem cells by whole genome sequencing

Ubiquitin-dependent control of hESC self-renewal and expansion

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  • Post published:May 9, 2025
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Human embryonic stem cells (hESCs) or induced pluripotent stem cells (iPSCs) provide an invaluable resource for regenerative medicine and disease modeling. To be able to use these cells in the…

Continue ReadingUbiquitin-dependent control of hESC self-renewal and expansion

Forming the Hematopoietic Niche from Human Pluripotent Stem Cells

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  • Post published:May 9, 2025
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The clinical potential of pluripotent stem cells for use in regenerative medicine will be realized only when the process by which tissues are generated from these cells is significantly more…

Continue ReadingForming the Hematopoietic Niche from Human Pluripotent Stem Cells

Biological relevance of microRNAs in hESC differentiation to endocrine pancreas

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  • Post published:May 9, 2025
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There remains an urgent and critical need for a cell-based cure of diabetes, one of the most costly diseases in California. Islet transplantation with persistent immune suppression has shown promise…

Continue ReadingBiological relevance of microRNAs in hESC differentiation to endocrine pancreas

Induced Pluripotent Stem Cells for Tissue Regeneration

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  • Post published:May 9, 2025
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Induced pluripotent stem cells (iPSCs) have tremendous potential for patient-specific cell therapies, which bypasses immune rejection issues and ethical concerns for embryonic stem cells (ESCs). However, to fully harness the…

Continue ReadingInduced Pluripotent Stem Cells for Tissue Regeneration

Engineering microscale tissue constructs from human pluripotent stem cells

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  • Post published:May 9, 2025
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Tissues derived from stem cells can serve multiple purposes to enhance biomedical therapies. Human tissues engineered from stem cells hold tremendous potential to serve as better substrates for the discovery…

Continue ReadingEngineering microscale tissue constructs from human pluripotent stem cells

Niche-Focused Research: Discovery & Development of Hematopoietic Regenerative Factors

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  • Post published:May 9, 2025
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Bone marrow and peripheral blood transplantation utilizing blood stem cells can provide curative treatment for patients with cancers and non-cancerous diseases of the blood and immune systems. Such treatments can…

Continue ReadingNiche-Focused Research: Discovery & Development of Hematopoietic Regenerative Factors

Molecular Imaging for Stem Cell Science and Clinical Application

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  • Post published:May 9, 2025
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Stem cells offer tremendous potential to treat previously intractable diseases. The clinical translation of these therapies, however, presents unique challenges. One challenge is the absence of robust methods to monitor…

Continue ReadingMolecular Imaging for Stem Cell Science and Clinical Application

Generation of functional cells and organs from iPSCs

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  • Post published:May 9, 2025
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The development of induced pluripotent stem cell (iPSC) technology may be the most important advance in stem cell biology for the future of medicine. This technology allows one to generate…

Continue ReadingGeneration of functional cells and organs from iPSCs

Epithelial progenitors and the stromal niche as therapeutic targets in lung disease

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  • Post published:May 9, 2025
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Chronic lung disease is an enormous societal and medical problem in California and the nation as a whole, representing the third most likely cause of death. Treatment costs were $389.2…

Continue ReadingEpithelial progenitors and the stromal niche as therapeutic targets in lung disease
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