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Injectable pro-regenerative scaffold for treating symptomatic peripheral artery disease

  • Post author:
  • Post published:June 4, 2025
  • Post category:

Translational Candidate Injectable biomaterial derived from the natural scaffolding of porcine muscle Area of Impact Improving the quality of life of patients with symptomatic peripheral artery disease. Mechanism of Action…

Continue ReadingInjectable pro-regenerative scaffold for treating symptomatic peripheral artery disease

Human iPSC-derived GABAergic Progenitors for Alzheimer’s Disease Treatment

  • Post author:
  • Post published:June 4, 2025
  • Post category:

Translational Candidate Human iPSC-derived GABAergic interneuron progenitors. Area of Impact Alzheimer's disease and related conditions. Mechanism of Action Transplantation of human iPSC-derived GABAergic progenitors, which will develop into mature GABAergic…

Continue ReadingHuman iPSC-derived GABAergic Progenitors for Alzheimer’s Disease Treatment

Curing Sickle cell Disease with CRISPR-Cas9 genome editing

  • Post author:
  • Post published:June 4, 2025
  • Post category:

Translational Candidate The principal objective of this program is to bring a Cas9-based gene editing cure for sickle cell disease to the pre-IND stage of development. Area of Impact The…

Continue ReadingCuring Sickle cell Disease with CRISPR-Cas9 genome editing

Curing Sickle cell Disease with CRISPR-Cas9 genome editing

  • Post author:
  • Post published:June 4, 2025
  • Post category:

Translational Candidate The principal objective of this program is to bring a Cas9-based gene editing cure for sickle cell disease to the pre-IND stage of development. Area of Impact The…

Continue ReadingCuring Sickle cell Disease with CRISPR-Cas9 genome editing

Pluripotent stem cell-derived chondrocytes for articular cartilage repair

  • Post author:
  • Post published:June 4, 2025
  • Post category:

Translational Candidate We propose to develop a universal, off-the-shelf treatment for articular cartilage repair based on pluripotent stem cell (PSC)-derived chondrospheres Area of Impact The proposed therapy could treat the…

Continue ReadingPluripotent stem cell-derived chondrocytes for articular cartilage repair

An autologous somatic stem cell therapy for the treatment of osteonecrosis

  • Post author:
  • Post published:June 4, 2025
  • Post category:

Translational Candidate An autologous somatic stem cell therapy for the treatment of osteonecrosis. Area of Impact Osteonecrosis is a painful, progressive disease for which there is no treatment, save replacing…

Continue ReadingAn autologous somatic stem cell therapy for the treatment of osteonecrosis

Personalized Cell Therapy for Diabetes

  • Post author:
  • Post published:June 4, 2025
  • Post category:

Translational Candidate Preclinical studies will develop patient specific stem cell-derived islets that secrete insulin & other islet hormones for regulation of blood sugar Area of Impact Genetically matched stem cell…

Continue ReadingPersonalized Cell Therapy for Diabetes

Personalized Cell Therapy for Diabetes

  • Post author:
  • Post published:June 4, 2025
  • Post category:

Translational Candidate Preclinical studies will develop patient specific stem cell-derived islets that secrete insulin & other islet hormones for regulation of blood sugar Area of Impact Genetically matched stem cell…

Continue ReadingPersonalized Cell Therapy for Diabetes

Human Embryonic Stem Cell-Derived Neural Stem Cell Transplants in Amyotrophic Lateral Sclerosis

  • Post author:
  • Post published:June 4, 2025
  • Post category:

Translational Candidate Spinal cord injections of human embryonic stem cell (hESC)-derived allogeneic neural stem cells (heNSCs) for treatment of ALS Area of Impact Treatment of Amyotrophic Lateral Sclerosis (ALS) Mechanism…

Continue ReadingHuman Embryonic Stem Cell-Derived Neural Stem Cell Transplants in Amyotrophic Lateral Sclerosis

Stem Cell-Based iNKT Cell Therapy for Cancer

  • Post author:
  • Post published:June 4, 2025
  • Post category:

Translational Candidate Lenti/iNKT-sr39TK Modified Autologous Human CD34+ Hematopoietic Stem Cells (HSCs) Area of Impact The targeted area of impact for the candidate is cancer therapy, in particular cancers that are…

Continue ReadingStem Cell-Based iNKT Cell Therapy for Cancer
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