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Cartilage Regeneration by the Chondrogenic Small Molecule PRO1 during Osteoarthritis

  • Post author:
  • Post published:August 17, 2026
  • Post category:

The ability to direct the differentiation of resident mesenchymal stem cells (MSCs) towards the cartilage lineage offers considerable promise for the regeneration of articular cartilage after traumatic joint injury or…

Continue ReadingCartilage Regeneration by the Chondrogenic Small Molecule PRO1 during Osteoarthritis

Preclinical development of a pan Bcl2 inhibitor for cancer stem cell directed therapy

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  • Post published:August 17, 2026
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Cancer is the leading cause of death for individuals under 85. Relapse and metastatic disease are the leading causes of cancer related mortality. Anti-apoptotic BCL2 family member overexpression has been…

Continue ReadingPreclinical development of a pan Bcl2 inhibitor for cancer stem cell directed therapy

Induction of immune tolerance after spinal grafting of human ES-derived neural precursors

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  • Post published:August 17, 2026
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Previous clinical studies have shown that grafting of human fetal brain tissue into the CNS of adult recipients can be associated with long-term (more then 10 years) graft survival even…

Continue ReadingInduction of immune tolerance after spinal grafting of human ES-derived neural precursors

A monoclonal antibody that depletes blood stem cells and enables chemotherapy free transplants

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  • Post published:August 16, 2026
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This trial proposes to replace SCID patients' dysfunctional immune cells with healthy ones using a safer form of bone marrow transplant (BMT). Current BMT procedures must use toxic chemotherapy to…

Continue ReadingA monoclonal antibody that depletes blood stem cells and enables chemotherapy free transplants

Retinal progenitor cells for treatment of retinitis pigmentosa

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  • Post published:August 16, 2026
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Retinitis pigmentosa (RP) is a severe form of blindness that runs in families with an incidence of 1:4000. A team at UC Irvine, is using cells called retinal progenitor cells…

Continue ReadingRetinal progenitor cells for treatment of retinitis pigmentosa

Regenerating the Acutely Infarcted Heart with iPSC-Ventricular Cardiomyocytes.

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  • Post published:August 16, 2026
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Continue ReadingRegenerating the Acutely Infarcted Heart with iPSC-Ventricular Cardiomyocytes.

A First-in-Class CIRSPR-CasX Gene Editing Therapy for Lowering Lp(a) to Prevent Cardiovascular Events

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  • Post published:August 16, 2026
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Continue ReadingA First-in-Class CIRSPR-CasX Gene Editing Therapy for Lowering Lp(a) to Prevent Cardiovascular Events

Gene Therapy for Alpha-1 Anti-Trypsin Deficiency

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  • Post published:August 16, 2026
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Continue ReadingGene Therapy for Alpha-1 Anti-Trypsin Deficiency

Late-stage development of AS-241, an UNC13A Targeting Antisense Oligonucleotide treatment for Amyotrophic Lateral Sclerosis, for IND-enabling studies

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  • Post published:August 16, 2026
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Continue ReadingLate-stage development of AS-241, an UNC13A Targeting Antisense Oligonucleotide treatment for Amyotrophic Lateral Sclerosis, for IND-enabling studies

Advancement of a myotropic, liver-detargeting therapy for LGMD2i/R9

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  • Post published:August 16, 2026
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Continue ReadingAdvancement of a myotropic, liver-detargeting therapy for LGMD2i/R9
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