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  • About
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Human Embryonic Stem Cell-Derived Cardiomyocytes for Patients with End Stage Heart Failure

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  • Post published:May 11, 2025
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Patients with end-stage heart failure have a 2-year survival rate of only 50% with conventional medical therapy. This dismal survival rate is actually significantly worse than patients with AIDS, liver…

Continue ReadingHuman Embryonic Stem Cell-Derived Cardiomyocytes for Patients with End Stage Heart Failure

Retinal progenitor cells for treatment of retinitis pigmentosa

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  • Post published:May 11, 2025
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The targeted disease is retinitis pigmentosa (RP), a severe form of blindness that often runs in families, but other times arises spontaneously from genetic errors. This disease is not overly…

Continue ReadingRetinal progenitor cells for treatment of retinitis pigmentosa

Restoration of memory in Alzheimer’s disease: a new paradigm using neural stem cell therapy

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  • Post published:May 11, 2025
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Alzheimer’s disease (AD), the leading cause of dementia, results in profound loss of memory and cognitive function, and ultimately death. In the US, someone develops AD every 69 seconds and…

Continue ReadingRestoration of memory in Alzheimer’s disease: a new paradigm using neural stem cell therapy

A monoclonal antibody that depletes blood stem cells and enables chemotherapy free transplants

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  • Post published:May 11, 2025
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Successful stem cell therapy requires the replacement of diseased or dysfunctional stem cells with healthy ones. These healthy stem cells can come from either a donor or can be stem…

Continue ReadingA monoclonal antibody that depletes blood stem cells and enables chemotherapy free transplants

Phase I study of IM Injection of VEGF-Producing MSC for the Treatment of Critical Limb Ischemia

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  • Post published:May 11, 2025
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Critical limb ischemia (CLI) represents a significant unmet medical need without any approved medical therapies for patients who fail surgical or angioplasty procedures to restore blood flow to the lower…

Continue ReadingPhase I study of IM Injection of VEGF-Producing MSC for the Treatment of Critical Limb Ischemia

Gene Correction of Autologous Hematopoietic Stem Cells in Artemis Deficient SCID

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  • Post published:May 11, 2025
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Artemis is a chemical in all cells in the body that is essential for the normal development of the immune system and repairing damaged DNA. Artemis deficiency (AD) causes Severe…

Continue ReadingGene Correction of Autologous Hematopoietic Stem Cells in Artemis Deficient SCID

Harnessing native fat-residing stem cells for bone regeneration

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  • Post published:May 11, 2025
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Like most tissues of the body, bone possesses a natural regenerative system aimed at restoring cells and tissues lost to natural cell aging, disease or injury. These natural regenerative systems…

Continue ReadingHarnessing native fat-residing stem cells for bone regeneration

Cartilage Regeneration by the Chondrogenic Small Molecule PRO1 during Osteoarthritis

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  • Post published:May 11, 2025
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The ability to direct the differentiation of resident mesenchymal stem cells (MSCs) towards the cartilage lineage offers considerable promise for the regeneration of articular cartilage after traumatic joint injury or…

Continue ReadingCartilage Regeneration by the Chondrogenic Small Molecule PRO1 during Osteoarthritis

Preclinical development of a pan Bcl2 inhibitor for cancer stem cell directed therapy

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  • Post published:May 11, 2025
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Cancer is the leading cause of death for individuals under 85. Relapse and metastatic disease are the leading causes of cancer related mortality. Anti-apoptotic BCL2 family member overexpression has been…

Continue ReadingPreclinical development of a pan Bcl2 inhibitor for cancer stem cell directed therapy

Induction of immune tolerance after spinal grafting of human ES-derived neural precursors

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  • Post published:May 11, 2025
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Previous clinical studies have shown that grafting of human fetal brain tissue into the CNS of adult recipients can be associated with long-term (more then 10 years) graft survival even…

Continue ReadingInduction of immune tolerance after spinal grafting of human ES-derived neural precursors
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