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Programmed Cell Death Pathways Activated in Embryonic Stem Cells

  • Post author:
  • Post published:May 9, 2025
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The therapeutic potential of human embryonic stem cells is extraordinary. Without a doubt, regenerative medicines will save thousands of lives in the years to come. Before that day arrives, much…

Continue ReadingProgrammed Cell Death Pathways Activated in Embryonic Stem Cells

Programs of alternative splicing regulation by polypyrimidine tract binding protein

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  • Post published:May 9, 2025
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The therapeutic promise of stem cell biology lies in its potential for cell replacement therapies in diseases where an essential cell type of the patient malfunctions or degenerates. This is…

Continue ReadingPrograms of alternative splicing regulation by polypyrimidine tract binding protein

RUNX1 in maintenance, expansion, and differentiation of therapeutic pluripotent stem cells

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  • Post published:May 9, 2025
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Recent technical advancements in human embryonic stem cell (ESC) and induced pluripotent stem cell (iPSC) production have revolutionized their potential applications in regenerative medicine. However, a remaining big hurdle in…

Continue ReadingRUNX1 in maintenance, expansion, and differentiation of therapeutic pluripotent stem cells

TCF-3: A Wnt Pathway Effector and Nanog Regulator in Pluripotent Stem Cell Self-Renewal

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  • Post published:May 9, 2025
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Despite the enormous potential for human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) for development of new treatments for human disease, there still remain important gaps…

Continue ReadingTCF-3: A Wnt Pathway Effector and Nanog Regulator in Pluripotent Stem Cell Self-Renewal

Cellular Reprogramming: Dissecting the Molecular Mechanism and Enhancing Efficiency

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  • Post published:May 9, 2025
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Pluripotent stem cells have a remarkable potential to develop into virtually any cell type of the body, making them a powerful tool for the study or direct treatment of human…

Continue ReadingCellular Reprogramming: Dissecting the Molecular Mechanism and Enhancing Efficiency

Systemic Protein Factors as Modulators of the Aging Neurogenic Niche

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  • Post published:May 9, 2025
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Approaches to repair the injured brain or even prevent age-related neurodegeneration are in their infancy but there is growing interest in the role of neural stem cells in these conditions.…

Continue ReadingSystemic Protein Factors as Modulators of the Aging Neurogenic Niche

Kinase signaling analysis of iPS cell reprogramming and differentiation

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  • Post published:May 9, 2025
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Like embryonic stem (ES) cells, induced pluripotent stem (iPS) cells can differentiate into every cell type in the body, providing enormous potential for regenerative medicine. Unlike ES cells, the derivation…

Continue ReadingKinase signaling analysis of iPS cell reprogramming and differentiation

The EphrinB2/EphB4 axis in regulating hESC pluripotency and differentiation

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  • Post published:May 9, 2025
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Human embryonic stem cells (hESC) have an inexhaustible ability to divide and renew, and under the appropriate conditions, differentiate and change into any cell type in the body. This balance…

Continue ReadingThe EphrinB2/EphB4 axis in regulating hESC pluripotency and differentiation

Differentiation of Human Embryonic Stem Cells into Urothelium

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  • Post published:May 9, 2025
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Augmentation or replacement of the bladder is often necessary for the treatment of adults with bladder cancer and children with spinal cord injury or spina bifida. Current surgical techniques utilize…

Continue ReadingDifferentiation of Human Embryonic Stem Cells into Urothelium

Novel Mechanism in Self-Renewal/Differentiation of Human Embryonic Stem Cells

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  • Post published:May 9, 2025
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The most prominent feature of the stem cell is its pluripotent capacity to differentiate into various types of cells. The importance of the orchestrated interplay between molecular regulators has been…

Continue ReadingNovel Mechanism in Self-Renewal/Differentiation of Human Embryonic Stem Cells
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