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Development of Induced Pluripotent Stem Cells for Modeling Human Disease

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  • Post published:December 13, 2025
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Human embryonic stem cells (hESC) hold great promise in regenerative medicine and cell replacement therapies because of their unique ability to self-renew and their developmental potential to form all cell…

Continue ReadingDevelopment of Induced Pluripotent Stem Cells for Modeling Human Disease

New Cell Lines for Huntington’s Disease

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  • Post published:December 13, 2025
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Huntington’s disease (HD) is a devastating neurodegenerative disease with a 1/10,000 disease risk that always leads to death. These numbers do not fully reflect the large societal and familial cost…

Continue ReadingNew Cell Lines for Huntington’s Disease

Understanding hESC-based Hematopoiesis for Therapeutic Benefit

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  • Post published:December 13, 2025
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Hematopoietic stem cell transplantation is the treatment of choice for many hematologic malignancies, and it is used to treat an expanding number of congenital blood disorders. However, only ~30% of…

Continue ReadingUnderstanding hESC-based Hematopoiesis for Therapeutic Benefit

Mechanisms to maintain the self-renewal and genetic stability of human embryonic stem cells

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  • Post published:December 13, 2025
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Human embryonic stem cells (hESCs) are capable of unlimited self-renewal, a process to reproduce self, and retain the ability to differentiate into all cell types in the body. Therefore, hESCs…

Continue ReadingMechanisms to maintain the self-renewal and genetic stability of human embryonic stem cells

Generation of inner ear sensory cells from human ES cells toward a cure for deafness

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  • Post published:December 13, 2025
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Hearing loss is the leading birth defect in the United States with ~3 children in 1,000 born with partial to profound compromise of auditory function. Debilitating hearing loss is estimated…

Continue ReadingGeneration of inner ear sensory cells from human ES cells toward a cure for deafness

Improved hES Cell Growth and Differentiation

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  • Post published:December 13, 2025
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Human embryonic stem (hES) cells are pluripotent stem cells that can theoretically give rise to every cell type in the human body. Consequently, hES cells have enormous promise for the…

Continue ReadingImproved hES Cell Growth and Differentiation

Guiding the developmental program of human embryonic stem cells by isolated Wnt factors

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  • Post published:December 13, 2025
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Just like cells in a human embryo, embryonic stem cells have the potential to give rise to all cell types and tissues in a human body. That is why it…

Continue ReadingGuiding the developmental program of human embryonic stem cells by isolated Wnt factors

Epigenetic gene regulation during the differentiation of human embryonic stem cells: Impact on neural repair

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  • Post published:December 13, 2025
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Human embryonic stem cells (hESCs) have the potential to become all sorts of cells in human body including nerve cells. Moreover, hESCs can be expanded in culture plates into a…

Continue ReadingEpigenetic gene regulation during the differentiation of human embryonic stem cells: Impact on neural repair

microRNA Regulation of Cardiomyocyte Differentiation from Human Embryonic Stem Cells

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  • Post published:December 13, 2025
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Regenerative therapies could be particularly beneficial for heart disease, which is the leading killer of adults in the U.S, and is responsible for the 5 million Americans with insufficient cardiac…

Continue ReadingmicroRNA Regulation of Cardiomyocyte Differentiation from Human Embryonic Stem Cells

Molecular and Cellular Transitions from ES Cells to Mature Functioning Human Neurons

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  • Post published:December 13, 2025
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Human embryonic stem cells (hESCs) are pluripotent entities, capable of generating a whole-body spectrum of distinct cell types. We have developmental procedures for inducing hESCs to develop into pure populations…

Continue ReadingMolecular and Cellular Transitions from ES Cells to Mature Functioning Human Neurons
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