Yang Xu
Institution Name:
University of California, San Diego
Total Awards:
4
Award Value:
$10,682,508
Awards as PI
Publications
- Cell Stem Cell 2010 Modeling disease in human ESCs using an efficient BAC-based homologous recombination system. (PubMed: 20074536)
- Trends Genet 2009 Genome integrity: linking pluripotency and tumorgenicity. (PubMed: 19801173)
- Trends Cell Biol 2010 p53 and stem cells: new developments and new concerns. (PubMed: 20061153)
- Proc Natl Acad Sci U S A 2010 Phosphorylation stabilizes Nanog by promoting its interaction with Pin1. (PubMed: 20622153)
- Discov Med 2010 Disease research and drug development models based on genetically altered human embryonic stem cells. (PubMed: 20587338)
- Regen Med 2011 Self-renewal and scalability of human embryonic stem cells for human therapy. (PubMed: 21548738)
- J Biol Chem 2012 A scalable approach to prevent teratoma formation of human embryonic stem cells. (PubMed: 22865887)
- Protein Cell 2012 The genomic stability of induced pluripotent stem cells. (PubMed: 22528751)
- Stem Cells 2012 Concise review: Immune recognition of induced pluripotent stem cells. (PubMed: 22419544)
- Genome Med 2012 Challenges to the clinical application of pluripotent stem cells: towards genomic and functional stability. (PubMed: 22741526)
- J Biol Chem 2011 Inhibitors of Src and focal adhesion kinase promote endocrine specification: impact on the derivation of beta-cells from human pluripotent stem cells. (PubMed: 21852242)
- Stem Cell Reports 2014 Mouse SCNT ESCs Have Lower Somatic Mutation Load Than Syngeneic iPSCs. (PubMed: 24749065)
- Cell Stem Cell 2014 An effective approach to prevent immune rejection of human ESC-derived allografts. (PubMed: 24388175)
- Cell Stem Cell 2015 Humanized Mice Reveal Differential Immunogenicity of Cells Derived from Autologous Induced Pluripotent Stem Cells. (PubMed: 26299572)
- Oncogene 2018 Artemisitene suppresses tumorigenesis by inducing DNA damage through deregulating c-Myc-topoisomerase pathway. (PubMed: 29795406)
- Stem Cells 2016 Brief Report: Immune Microenvironment Determines the Immunogenicity of Induced Pluripotent Stem Cell Derivatives. (PubMed: 26439188)