Tracy Grikscheit
Institution Name:
Children's Hospital of Los Angeles
Total Awards:
2
Award Value:
$6,357,282
Awards as PI
| Program Type | Institution | Grant Title | Award Value |
|---|---|---|---|
| New Faculty II | Children's Hospital of Los Angeles | Mechanism of Tissue Engineered Small Intestine Formation | $3,211,122 |
| New Faculty Physician Scientist | Children's Hospital of Los Angeles | The generation and expansion of tissue-engineered small intestine from human stem/ progenitor cells: a preclinical study of functional translation | $3,146,160 |
Total: $6,357,282.00 |
Publications
- Development 2011 FGF10 controls the patterning of the tracheal cartilage rings via Shh. (PubMed: 21148187)
- J Surg Res 2009 Tissue-engineered small intestine and stomach form from autologous tissue in a preclinical large animal model. (PubMed: 19665143)
- J Surg Res 2009 Wnt5a knock-out mouse as a new model of anorectal malformation. (PubMed: 19577771)
- Regen Med 2011 VEGF optimizes the formation of tissue-engineered small intestine. (PubMed: 21916592)
- Curr Opin Pediatr 2012 Tissue-engineering of the gastrointestinal tract. (PubMed: 22450251)
- Expert Rev Med Devices 2011 Tissue-engineered small intestine. (PubMed: 22029464)
- Dev Biol 2012 FGF9-Pitx2-FGF10 signaling controls cecal formation in mice. (PubMed: 22819677)
- J Vis Exp 2012 Tissue engineering of the intestine in a murine model. (PubMed: 23222891)
- Regen Med 2012 Human tissue-engineered colon forms from postnatal progenitor cells: an in vivo murine model. (PubMed: 23164081)
- PLoS One 2012 Fibroblast growth factor 10-fibroblast growth factor receptor 2b mediated signaling is not required for adult glandular stomach homeostasis. (PubMed: 23133671)
- Clin Gastroenterol Hepatol 2013 Tissue Engineering the Small Intestine. (PubMed: 23380001)
- Methods Mol Biol 2013 A "living bioreactor" for the production of tissue-engineered small intestine. (PubMed: 23494439)
- Semin Pediatr Surg 2013 Tissue engineering: a promising therapeutic approach to necrotizing enterocolitis. (PubMed: 23611615)
- J Tissue Eng Regen Med 2013 Fgf10 overexpression enhances the formation of tissue-engineered small intestine. (PubMed: 23468377)
- J Pediatr Surg 2013 Human tissue-engineered small intestine forms from postnatal progenitor cells. (PubMed: 23331805)
- Tissue Eng Part A 2014 Murine and human tissue-engineered esophagus form from sufficient stem/progenitor cells and do not require microdesigned biomaterials. (PubMed: 25298083)
- Biol Open 2015 Generation of tissue-engineered small intestine using embryonic stem cell-derived human intestinal organoids. (PubMed: 26459240)
- Am J Physiol Gastrointest Liver Physiol 2015 Human and mouse tissue-engineered small intestine both demonstrate digestive and absorptive function. (PubMed: 25573173)
- Semin Pediatr Surg 2014 Stem cells and biopharmaceuticals: vital roles in the growth of tissue-engineered small intestine. (PubMed: 24994528)
- Stem Cell Reports 2017 Neural Crest Cell Implantation Restores Enteric Nervous System Function and Alters the Gastrointestinal Transcriptome in Human Tissue-Engineered Small Intestine. (PubMed: 28803915)
- Cold Spring Harb Perspect Med 2017 Tissue Engineering Functional Gastrointestinal Regions: The Importance of Stem and Progenitor Cells. (PubMed: 28320829)
- Cell Stem Cell 2017 Created of Warm Blood and Nerves: Restoring an Enteric Nervous System in Organoids. (PubMed: 28061353)
- Exp Physiol 2018 Short-term and long-term human or mouse organoid units generate tissue-engineered small intestine without added signalling molecules. (PubMed: 30232817)
- J Pediatr Surg 2018 Stem cells for babies and their surgeons: the future is now. (PubMed: 30497818)
- Am J Physiol Gastrointest Liver Physiol 2020 Grading TESI: Crypt and villus formation in tissue-engineered small intestine alters with stem/progenitor cell source. (PubMed: 32597710)
- Am J Physiol Gastrointest Liver Physiol 2021 N-terminal deletion of specific phosphorylation sites on PHOX2B disrupts the formation of enteric neurons in vivo. (PubMed: 33881351)