Awards as PI
| Program Type | Institution | Grant Title | Award Value |
|---|---|---|---|
| Early Translational II | Stanford University | Stem Cell Therapy for Duchenne Muscular Dystrophy | $2,267,261 |
| New Cell Lines | Stanford University | Safe, efficient creation of human induced pluripotent stem cells without the use of retroviruses | $1,406,875 |
| Tools and Technologies II | Stanford University | Site-specific integration of Lmx1a, FoxA2, & Otx2 to optimize dopaminergic differentiation | $1,592,897 |
| Early Translational IV | Stanford University | Engineered iPSC for therapy of limb girdle muscular dystrophy type 2B | $1,876,253 |
Total: $7,143,286.00 |
Publications
- Expert Opin Biol Ther 2011 The therapeutic potential of phiC31 integrase as a gene therapy system. (PubMed: 21736536)
- Curr Gene Ther 2011 Therapeutic applications of the PhiC31 integrase system. (PubMed: 21888619)
- Biotechnol J 2012 Efficient reversal of phiC31 integrase recombination in mammalian cells. (PubMed: 22933343)
- Biol Open 2014 Serine integrase chimeras with activity in E. coli and HeLa cells. (PubMed: 25217617)
- Nucleic Acids Res 2013 DICE, an efficient system for iterative genomic editing in human pluripotent stem cells. (PubMed: 24304893)
- PLoS One 2014 Recombinase-Mediated Reprogramming and Dystrophin Gene Addition in mdx Mouse Induced Pluripotent Stem Cells. (PubMed: 24781921)
- Methods Mol Biol 2015 Using phage integrases in a site-specific dual integrase cassette exchange strategy. (PubMed: 25408400)
- Nucleic Acids Res 2016 In vivo blunt-end cloning through CRISPR/Cas9-facilitated non-homologous end-joining. (PubMed: 26762978)
- Mol Ther 2016 Precise Correction of Disease Mutations in Induced Pluripotent Stem Cells Derived From Patients With Limb Girdle Muscular Dystrophy. (PubMed: 26916285)
- N Engl J Med 2016 The CRISPR Way to Think about Duchenne's. (PubMed: 27119241)
- Biotechnol J 2017 Genomic integration of the full-length dystrophin coding sequence in Duchenne muscular dystrophy induced pluripotent stem cells. (PubMed: 28139886)
- Methods Mol Biol 2017 Use of the DICE (Dual Integrase Cassette Exchange) System. (PubMed: 28815494)
- Mol Ther Methods Clin Dev 2017 DNA-Mediated Gene Therapy in a Mouse Model of Limb Girdle Muscular Dystrophy 2B. (PubMed: 29159199)