Judith Shizuru

Institution Name:

Stanford University

Total Awards:

4

Award Value:

$23,818,706

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Awards as PI

Program Type	Institution	Grant Title	Award Value
Transplantation Immunology	Stanford University	Purified allogeneic hematopoietic stem cells as a platform for tolerance induction	$1,233,275
Disease Team Therapy Planning I	Stanford University	A monoclonal antibody that depletes blood stem cells and enables chemotherapy free transplants	$90,147
Disease Team Therapy Development - Research	Stanford University	A monoclonal antibody that depletes blood stem cells and enables chemotherapy free transplants	$19,068,382
Clinical Trial Stage Projects	Stanford University	A monoclonal antibody that depletes blood stem cells and enables chemotherapy free transplants	$3,426,902
			Total: $23,818,706.00

Awards as Co-PI

Tools and Technologies III

Identification and isolation of transplantable human hematopoietic stem cells from pluripotent cell lines; two steps from primitive hematopoiesis to transplantable definitive cells, and non-toxic conditioning of hosts for hematopoeitic stem cell transp...

Publications

Curr Opin Immunol 2012 The road to purified hematopoietic stem cell transplants is paved with antibodies. (PubMed: 22939368)
Sci Transl Med 2016 Hematopoietic stem cell transplantation in immunocompetent hosts without radiation or chemotherapy. (PubMed: 27510901)
Blood 2019 Anti-human CD117 antibody-mediated bone marrow niche clearance in nonhuman primates and humanized NSG mice. (PubMed: 30617195)
Blood 2019 Anti-CD117 antibody depletes normal and myelodysplastic syndrome human hematopoietic stem cells in xenografted mice. (PubMed: 30745302)
Nat Commun 2019 Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation. (PubMed: 30728354)
Cell Stem Cell 2019 Antibody Conditioning Enables MHC-Mismatched Hematopoietic Stem Cell Transplants and Organ Graft Tolerance. (PubMed: 31204177)