April Pyle

Institution Name:

University of California, Los Angeles

Total Awards:

3

Award Value:

$4,529,319

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Awards as PI

Program Type	Institution	Grant Title	Award Value
Inception - Discovery Stage Research Projects	University of California, Los Angeles	Novel Platforms to Enhance In Vivo Delivery of Skeletal Muscle Progenitor Cells from Human Pluripotent Stem Cells	$230,400
Quest - Discovery Stage Research Projects	University of California, Los Angeles	CRISPR/Cas9 nanoparticle enabled therapy for Duchenne Muscular Dystrophy in muscle stem cells	$2,150,400
Quest - Discovery Stage Research Projects	University of California, Los Angeles	Identification and Generation of Long Term Repopulating Human Muscle Stem Cells from Human Pluripotent Stem Cells	$2,148,519
			Total: $4,529,319.00

Publications

J Neuromuscul Dis 2017 Creation of a Novel Humanized Dystrophic Mouse Model of Duchenne Muscular Dystrophy and Application of a CRISPR/Cas9 Gene Editing Therapy. (PubMed: 28505980)
Nat Cell Biol 2018 ERBB3 and NGFR mark a distinct skeletal muscle progenitor cell in human development and hPSCs. (PubMed: 29255171)
Cell Stem Cell 2020 A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells. (PubMed: 32396864)