Enhancing clinical predictability with novel models of iPSC-derived nociceptor for chronic pain

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Grant Award Details

Grant Number:
DISC0-17976
Investigator(s):
Institution:
Type:
PI

Award Value:
$1,498,623
Status:
Pre-Active

Grant Application Details

Application Title:

Enhancing clinical predictability with novel models of iPSC-derived nociceptor for chronic pain

Public Abstract:
Research Objective

1.- Develop a better chronic pain in vitro model using iPSC-derived nociceptors.
2.- Understand the Mechanism of Action behind Chronic Pain Nociception.
3.- Attributes to establish a robust model.

Impact

Translating pain drugs is limited by in vitro model relevance. We propose a novel human iPSC-derived nociceptor model that can provide enhanced clinical predictability for chronic pain.