Development of in vitro and in vivo functional human synthetic kidney organoid (hSKO) model as a platform technology for kidney research

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Grant Award Details

Grant Number:
DISC0-17626
Investigator(s):
Name:
Type:
PI

Award Value:
$2,287,926
Status:
Pre-Active

Grant Application Details

Application Title:

Development of in vitro and in vivo functional human synthetic kidney organoid (hSKO) model as a platform technology for kidney research

Public Abstract:
Research Objective

Development of a human stem cell-derived, spatially-patterned, mature and functional human synthetic kidney organoid (hSKO) model as a platform technology for basic and translational kidney research.

Impact

Lack of a reliable human kidney model is a major bottleneck in kidney research. This project will establish the most physiologically relevant model for studying human kidney development and disease.