Human Stem Cell Use: SCNT

Patient-specific cells with nuclear transfer

Somatic cell nuclear transfer (NT) is a powerful research tool with the potential for creating unique cell and tissue sources for studies of disease pathogenesis and regenerative medicine. Creation of pluripotent mouse embryonic stem (ES) cells using NT has been achieved and the prospects for generating human ES cells by NT are promising. However, there […]

Maturation of Human Oocytes for SCNT and Embryonic Stem Cell Derivation

A major issue for tissue and cell therapy in regenerative medicine is the immune rejection of grafts originated from a non-compatible individual. Mature eggs contain factors essential for the re-programming of cell nuclei from patients to allow the establishment of patient-compatible pluripotent stem cells for the treatment of diverse degenerative diseases. Although up to half […]