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Epigenetic gene regulation during the differentiation of human embryonic stem cells: Impact on neural repair

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  • Post published:May 21, 2025
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Human embryonic stem cells (hESCs) have the potential to become all sorts of cells in human body including nerve cells. Moreover, hESCs can be expanded in culture plates into a…

Continue ReadingEpigenetic gene regulation during the differentiation of human embryonic stem cells: Impact on neural repair

Using Human Embryonic Stem Cells to Understand and to Develop New Therapies for Alzheimer’s Disease

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  • Post published:May 21, 2025
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Alzheimer’s Disease (AD) is a progressive incurable disease that robs people of their memory and ability to think and reason. It is emotionally, and sometimes financially devastating to families that…

Continue ReadingUsing Human Embryonic Stem Cells to Understand and to Develop New Therapies for Alzheimer’s Disease

Modeling Human Embryonic Development with Human Embryonic Stem Cells

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  • Post published:May 21, 2025
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Stem cells have entered the public consciousness as “cells that can do anything” and have been hailed as a panacea in the fight against disease, aging and cancer. Unfortunately, we…

Continue ReadingModeling Human Embryonic Development with Human Embryonic Stem Cells

Reprogramming Differentiated Human Cells to a Pluripotent State

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  • Post published:May 21, 2025
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If the therapeutic potential of human embryonic stem (ES) cells is to be realized, the ability to produce pluripotent stem cells with defined genetic backgrounds is essential. Pluripotent cells, through…

Continue ReadingReprogramming Differentiated Human Cells to a Pluripotent State

RUNX1 in maintenance, expansion, and differentiation of therapeutic pluripotent stem cells

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  • Post published:May 21, 2025
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Recent technical advancements in human embryonic stem cell (ESC) and induced pluripotent stem cell (iPSC) production have revolutionized their potential applications in regenerative medicine. However, a remaining big hurdle in…

Continue ReadingRUNX1 in maintenance, expansion, and differentiation of therapeutic pluripotent stem cells

TCF-3: A Wnt Pathway Effector and Nanog Regulator in Pluripotent Stem Cell Self-Renewal

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  • Post published:May 21, 2025
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Despite the enormous potential for human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) for development of new treatments for human disease, there still remain important gaps…

Continue ReadingTCF-3: A Wnt Pathway Effector and Nanog Regulator in Pluripotent Stem Cell Self-Renewal

Cellular Reprogramming: Dissecting the Molecular Mechanism and Enhancing Efficiency

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  • Post published:May 21, 2025
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Pluripotent stem cells have a remarkable potential to develop into virtually any cell type of the body, making them a powerful tool for the study or direct treatment of human…

Continue ReadingCellular Reprogramming: Dissecting the Molecular Mechanism and Enhancing Efficiency

Systemic Protein Factors as Modulators of the Aging Neurogenic Niche

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  • Post published:May 21, 2025
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Approaches to repair the injured brain or even prevent age-related neurodegeneration are in their infancy but there is growing interest in the role of neural stem cells in these conditions.…

Continue ReadingSystemic Protein Factors as Modulators of the Aging Neurogenic Niche

Kinase signaling analysis of iPS cell reprogramming and differentiation

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  • Post published:May 21, 2025
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Like embryonic stem (ES) cells, induced pluripotent stem (iPS) cells can differentiate into every cell type in the body, providing enormous potential for regenerative medicine. Unlike ES cells, the derivation…

Continue ReadingKinase signaling analysis of iPS cell reprogramming and differentiation

The function of YAP in human embryonic stem cells

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  • Post published:May 21, 2025
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Embryonic stem cells have the potential to generate all tissue types that could be used for regenerative medicine, such as replacement of damaged neurons, replenish of insulin secreting beta cells,…

Continue ReadingThe function of YAP in human embryonic stem cells
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