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Human pluripotent stem cell-based therapeutics for preeclampsia

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  • Post published:December 5, 2025
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Preeclampsia (PE) is a pregnancy complication, characterized by high blood pressure and abnormal kidney function, which affects 5-8% of all pregnancies. It is responsible for a significant proportion of maternal…

Continue ReadingHuman pluripotent stem cell-based therapeutics for preeclampsia

Epigenetic regulation of human cardiac differentiation

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  • Post published:December 5, 2025
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Each cell type in our body has its own identity. This identity allows a heart cell to contract repetitively, and a brain cell to conduct nerve impulses. Each cell type…

Continue ReadingEpigenetic regulation of human cardiac differentiation

3D Modeling of Retina using Polymer Scaffolds for Understanding Disease Pathogenesis

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  • Post published:December 5, 2025
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Inherited retinal degenerations result in visual loss in patients as early as in their adolescence. Retinitis Pigmentosa includes a group of such degenerations which run in families and can result…

Continue Reading3D Modeling of Retina using Polymer Scaffolds for Understanding Disease Pathogenesis

Investigation of the role of O-GlcNAcylation in SOX2 function during reprogramming

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  • Post published:December 5, 2025
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Induced pluripotent stem cells (iPSCs) are a potential source of material for cell replacement therapies. Thus, achieving maximal efficiency of reprogramming will be important for cellular medicine. In this submission…

Continue ReadingInvestigation of the role of O-GlcNAcylation in SOX2 function during reprogramming

Induction of Pluripotent Stem Cell-Derived Pacemaking Cells

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  • Post published:December 5, 2025
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Currently, over 350,000 patients per year with abnormal heart rhythm receive electronic pacemakers to restore their normal heart beat. Electronic pacemakers do not respond to the need for changing heart…

Continue ReadingInduction of Pluripotent Stem Cell-Derived Pacemaking Cells

Studying Arrhythmogenic Right Ventricular Dysplasia with patient-specific iPS cells

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  • Post published:December 5, 2025
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Most heart conditions leading to sudden death or impaired pumping heart functions in the young people (

Continue ReadingStudying Arrhythmogenic Right Ventricular Dysplasia with patient-specific iPS cells

Transcriptional regulation of pluripotency in human embryonic stem cells

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  • Post published:December 5, 2025
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All of the diverse cells in the human body contain the same genetic information, and originally arose from a single cell, a fertilized egg. Embryogenesis is a result of cell…

Continue ReadingTranscriptional regulation of pluripotency in human embryonic stem cells

Common molecular mechanisms in neurodegenerative diseases using patient based iPSC neurons

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  • Post published:December 5, 2025
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A major medical problem in CA is the growing population of individuals with neurodegenerative diseases, including Parkinson’s (PD) and Huntington’s (HD) disease. These diseases affect millions of people, sometimes during…

Continue ReadingCommon molecular mechanisms in neurodegenerative diseases using patient based iPSC neurons

Energy metabolism and aging pathways in human stem cell reprogramming and differentiation

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  • Post published:December 5, 2025
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The discovery that human skin cells can be reprogrammed into stem cells holds great promise for therapies for degenerative diseases. As many patients in need of regenerative medicine therapies are…

Continue ReadingEnergy metabolism and aging pathways in human stem cell reprogramming and differentiation

Stem cell models to analyze the role of mutated C9ORF72 in neurodegeneration

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  • Post published:December 5, 2025
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Amyotrophic lateral sclerosis (ALS) is an idiopathic adult-onset degenerative disease characterized by progressive weakness from loss of upper and lower motor neurons. Onset is insidious, progression is essentially linear, and…

Continue ReadingStem cell models to analyze the role of mutated C9ORF72 in neurodegeneration
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