Shared Resource Laboratory for Stem Cell-Based Modeling: Resources for Exploring the Biological Underpinnings of Aging and Age-Associated Pathologies

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We seek to engage more Californians in stem cell research by providing access to cell models (including those for modeling the aging brain) derived from a uniquely characterize human cohort,…

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Unraveling nuclear Tau functions using age-equivalent human induced neurons from healthy aging donors and tauopathy patients

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Research Objective This project investigates how normal tau protein protects aging neurons. We'll use aging human neurons to understand how tau helps repairing DNA and why this protection fails disease.…

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