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Center of Excellence for Stem Cell Genomics – Stanford

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  • Post published:June 5, 2025
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The Center of Excellence in Stem Cell Genomics will bring together investigators from seven major California research institutions to bridge two fields – genomics and pluripotent stem cell research. The…

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Mass Cytometry to Delineate the Human Muscle Stem Cell Hierarchy and Dysfunction in Aging

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  • Post published:June 5, 2025
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Aging is characterized by a decline in skeletal muscle mass and strength (sarcopenia), coupled with an accumulation of fat tissue, impairing mobility and quality of life in 45% of individuals…

Continue ReadingMass Cytometry to Delineate the Human Muscle Stem Cell Hierarchy and Dysfunction in Aging

Non-invasive live imaging of stem cell signature metabolic states

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  • Post published:June 5, 2025
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Stem cells in tissues exhibit unique metabolic states that could distinguish them from other more specialized cells. Using a new type of microscopy we can image the metabolic states of…

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Molecular regulation of stem cell potency

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  • Post published:June 5, 2025
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The field of stem cell biology as it applies to regenerative medicine requires a detailed understanding of what controls stem cell function. Our fundamental interest is in the molecular pathways…

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Innate Immune Regulation of Lung Alveolar Stem Cell Renewal in Mouse and Man

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  • Post published:June 5, 2025
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The lung, along with the skin and gut are the three organs in perpetual contact with our environment. The lung has evolved mechanisms for repairing injury due to exogenous noxious…

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A novel druggable mechanism to safeguard stem cell genome

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  • Post published:June 5, 2025
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Safeguarding the genome is essential for cells’ proper functions, and more importantly for safe and efficacious applications involving pluripotent stem cells and adult stem cells. However, how pluripotent or somatic…

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Molecular basis of plasma membrane characteristics reflecting stem cell fate potential

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  • Post published:June 5, 2025
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Stem cells generate mature, functional cells after proteins on the cell surface interact with cues from the environment encountered during development or after transplantation. Thus, these cell surface proteins are…

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New Regulators of Spermatogonial Stem Cells: RHOX Homeobox Transcription Factors

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  • Post published:June 5, 2025
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Infertility afflicts a remarkably high percentage (~15%) of couples, with male factor defects being responsible for more than ½ of these cases. One-third of these male infertility cases have no…

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Differentiation of Human Hematopoietic Stem Cells into iNKT Cells

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  • Post published:June 5, 2025
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Blood stem cells living in the bone marrow of adult humans give rise to all of the cells in our blood, including the red blood cells that carry oxygen to…

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Tissue Engineered Recellularized Laryngotracheal Implants

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  • Post published:June 5, 2025
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The goal is to bring a safe and effective therapy to adult patients with critical narrowing of the upper windpipe (trachea) and lower voicebox (larynx). Our intent is to implement…

Continue ReadingTissue Engineered Recellularized Laryngotracheal Implants
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