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Embryonic stem cell-based generation of rat models for assessing human cellular therapies

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  • Post published:August 15, 2026
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Heart failure, diabetes and neurodegenerative diseases are among the leading causes of death and disability worldwide. These diseases are characterized by the loss of specific cell types and can be…

Continue ReadingEmbryonic stem cell-based generation of rat models for assessing human cellular therapies

A small molecule tool for reducing the malignant potential in reprogramming human iPSCs and ESCs

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  • Post published:August 15, 2026
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This research project aims to solve a key bottleneck in the use of differentiated human embryonic stem cells and induced pluripotent stem cells for the regeneration and replacement of diseased…

Continue ReadingA small molecule tool for reducing the malignant potential in reprogramming human iPSCs and ESCs

Biophysical Determinants of Early Embryonic Stem Cell Fate Specification

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  • Post published:August 15, 2026
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Regenerative therapies require effective differentiation of stem cells to cell types that are functionally identical to those found in vivo. Many current differentiation protocols merely involve optimization of proteins added…

Continue ReadingBiophysical Determinants of Early Embryonic Stem Cell Fate Specification

Single Molecule Biophysics and Biology of Cellular Identity

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  • Post published:August 15, 2026
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One of your earliest childhood biology lessons probably occurred when your body demonstrated to you that your skin is an organ that is able to self-regenerate. Indeed wound healing is…

Continue ReadingSingle Molecule Biophysics and Biology of Cellular Identity

Advancing ISP-001 for Mucopolysaccharidosis I: Clinical Expansion, Clinical Manufacturing and Release Testing

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  • Post published:August 14, 2026
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Continue ReadingAdvancing ISP-001 for Mucopolysaccharidosis I: Clinical Expansion, Clinical Manufacturing and Release Testing

Phase 1/2 Study to Evaluate the Safety, Tolerability, and Efficacy of MZ-1866, a gene therapy for Pitt Hopkins Syndrome

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  • Post published:August 14, 2026
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Continue ReadingPhase 1/2 Study to Evaluate the Safety, Tolerability, and Efficacy of MZ-1866, a gene therapy for Pitt Hopkins Syndrome

Phase I/II Clinical Trial for CMT4J

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  • Post published:August 14, 2026
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Continue ReadingPhase I/II Clinical Trial for CMT4J

Personalized antisense oligonucleotide therapy for rare pediatric genetic disease: SCN2A

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  • Post published:August 14, 2026
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Continue ReadingPersonalized antisense oligonucleotide therapy for rare pediatric genetic disease: SCN2A

CRISPR/Cas9-mediated gene editing of Hematopoietic stem and progenitor cells for Friedreich’s ataxia

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  • Post published:August 14, 2026
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Continue ReadingCRISPR/Cas9-mediated gene editing of Hematopoietic stem and progenitor cells for Friedreich’s ataxia

Advancing Therapeutic Discovery Through Multimodal Analyses of Genetic and Cellular Mechanisms in Neuropsychiatric Disorders

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  • Post published:August 14, 2026
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Continue ReadingAdvancing Therapeutic Discovery Through Multimodal Analyses of Genetic and Cellular Mechanisms in Neuropsychiatric Disorders
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