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Epigenetic gene regulation during the differentiation of human embryonic stem cells: Impact on neural repair

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  • Post published:June 29, 2025
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Human embryonic stem cells (hESCs) have the potential to become all sorts of cells in human body including nerve cells. Moreover, hESCs can be expanded in culture plates into a…

Continue ReadingEpigenetic gene regulation during the differentiation of human embryonic stem cells: Impact on neural repair

Spinal ischemic paraplegia: modulation by human embryonic stem cell implant.

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  • Post published:June 29, 2025
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schemia-induced paraplegia often combined with a qualitatively defined increase in muscle tone (i.e. spasticity and rigidity) is a serious complication associated with a temporary aortic cross-clamping ( a surgical procedure…

Continue ReadingSpinal ischemic paraplegia: modulation by human embryonic stem cell implant.

Molecular and Cellular Transitions from ES Cells to Mature Functioning Human Neurons

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  • Post published:June 29, 2025
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Human embryonic stem cells (hESCs) are pluripotent entities, capable of generating a whole-body spectrum of distinct cell types. We have developmental procedures for inducing hESCs to develop into pure populations…

Continue ReadingMolecular and Cellular Transitions from ES Cells to Mature Functioning Human Neurons

Derivation of Inhibitory Nerve Cells from Human Embryonic Stem Cells

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  • Post published:June 29, 2025
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Parkinson’s disease (PD) is caused by degeneration of a specific population of dopamine-producing nerve cells in the brain and is chronic, progressive, and incurable. Loss of dopamine-containing cells results in…

Continue ReadingDerivation of Inhibitory Nerve Cells from Human Embryonic Stem Cells

Using Human Embryonic Stem Cells to Understand and to Develop New Therapies for Alzheimer’s Disease

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  • Post published:June 29, 2025
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Alzheimer’s Disease (AD) is a progressive incurable disease that robs people of their memory and ability to think and reason. It is emotionally, and sometimes financially devastating to families that…

Continue ReadingUsing Human Embryonic Stem Cells to Understand and to Develop New Therapies for Alzheimer’s Disease

Human Embryonic Stem Cells and Remyelination in a Viral Model of Demyelination

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  • Post published:June 29, 2025
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Multiple sclerosis (MS) is the most common neurologic disease affecting young adults under the age of 40 with the majority of MS patients diagnosed in the second or third decade…

Continue ReadingHuman Embryonic Stem Cells and Remyelination in a Viral Model of Demyelination

Genetic manipulation of human embryonic stem cells and its application in studying CNS development and repair

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  • Post published:June 29, 2025
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The advent of human embryonic stem cells (hESCs) has offered enormous potential for regenerative medicine and for basic understanding of human biology. On the one hand, hESCs can be turned…

Continue ReadingGenetic manipulation of human embryonic stem cells and its application in studying CNS development and repair

Modeling Parkinson’s Disease Using Human Embryonic Stem Cells

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  • Post published:June 29, 2025
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Parkinson’s disease (PD) is the most frequent neurodegenerative movement disorder caused by damage of dopamine-producing nerve cells (DA neuron) in patient brain. The main symptoms of PD are age-dependent tremors…

Continue ReadingModeling Parkinson’s Disease Using Human Embryonic Stem Cells

Gene regulatory mechanisms that control spinal neuron differentiation from hES cells.

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  • Post published:June 29, 2025
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More than 600 disorders afflict the nervous system. Common disorders such as stroke, epilepsy, Parkinson’s disease and autism are well-known. Many other neurological disorders are rare, known only to the…

Continue ReadingGene regulatory mechanisms that control spinal neuron differentiation from hES cells.

Development of human ES cell lines as a model system for Alzheimer disease drug discovery

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  • Post published:June 29, 2025
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Alzheimer disease (AD) is a progressive neurodegenerative disorder that currently affects over 4.5 million Americans. By the middle of the century, the prevalence of AD in the USA is projected…

Continue ReadingDevelopment of human ES cell lines as a model system for Alzheimer disease drug discovery
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