Disease Focus: Intestinal Disease

Mechanism of Tissue Engineered Small Intestine Formation

Short Bowel Syndrome is an expensive, morbid condition with an increasing incidence. Fundamental congenital and perinatal conditions such as gastroschisis, malrotation, atresia, and necrotizing enterocolitis (NEC) may lead to short bowel syndrome (SBS). NEC is the most common gastrointestinal emergency in neonates and primarily occurs in premature infants As rates of prematurity are increasing, so […]

Differentiation of Human Embryonic Stem Cells to Intestinal Fates

The roughly 25 feet of intestine in the adult human play numerous essential roles in daily life, such as nutrient absorption, secretion of hormones, and serving as a barrier to infection. Commensurate with these diverse roles, diseases of the intestine are a considerable source of human morbidity and mortality. Indeed, numerous pathologic conditions including inflammatory […]

Inflammatory Bowel Disease and Stem Cell Research – Ophir Klein, UCSF

In his presentation to CIRM’s governing Board, Dr. Ophir Klein, a CIRM grantee and UCSF researcher, detailed his lab’s work to understand how stem cells regulate the healing of the intestine and to eventually find cures for inflammatory bowel disease (IBD).

Living with (IBD) Inflammatory Bowel Disease – Rachel Bonner, Hope for Crohn’s

She doesn’t want your sympathy. She doesn’t want your admiration. She just wants your understanding.   Rachel Bonner, a sixteen-year-old high school student and founder of the Hope for Crohn’s charity, spoke to the CIRM’s governing Board on September 10th about what it’s like living with Crohn’s disease.

Michael Rothenberg, Stanford – CIRM Stem Cell #SciencePitch

Justin Wagner, UCLA – CIRM Stem Cell #SciencePitch