Disease Focus: Heart Disease

Deepak Srivastava, Gladstone Institutes – CIRM Stem Cell #SciencePitch

Spotlight on Stem Cell Advances in Pediatric Heart Disease: A Change of Heart

One percent of live births have heart defects, the leading noninfectious cause of death in the 1st year. Using embryonic stem cell technology, Dr. Deepak Srivastava’s lab has made many insights into understand the genetic networks that control heart development as well the genetic mutations that are involved in heart defects. With these findings in […]

Spotlight on Stem Cell Advances in Heart Disease: Generating Muscle within an Existing Heart

Long-term stem cell-based strategies for heart disease aim to rebuild parts of the heart. But investigators like Deepak Srivastava are also looking into more near term goals to regenerate heart muscle from within the existing heart through direct reprogramming. Dr. Srivastava spoke about his recent work in this area to the CIRM Governing Board during […]

Joshua’s Heart Story: Pediatric Heart Disease and the Promise of Stem Cell Advances

The day before 9/11,  just four months pregnant, Mary Goulart and her husband learned through ultrasounds that their baby had several heart defects including a missing left ventricle. After birth, baby Joshua endured three open-heart surgeries and a massive stroke. Through years of various therapies and true determination, Joshua met his challenges with many accomplishments.  […]

Stem Cell Clinical Trial for Heart Failure: Eduardo Marbán – CIRM Spotlight on Disease

CIRM has funded a $5.5 million Disease Team to develop a follow-on cardiac stem cell clinical trial that uses a patient’s own heart stem cells to regenerate scarred tissue damaged by a heart attack. The team is led by Eduardo Marbán, MD, PhD, Director of the Cedars-Sinai Heart Institute. Marbán presented the team’s latest progress […]

Cardiovascular Therapies: Spotlight on Stem Cell Research – Welcoming Remarks

Robert Klein, J.D. and Claire Pomeroy, M.D., M.B.A., gave the welcoming remarks for the “Spotlight on Cardiovascular Therapies,” an educational event presented at the California Institute for Regenerative Medicine Governing Board meeting on March 10, 2011 in Burlingame, CA. Klein is Chair of the CIRM Governing Board. Pomeroy is Vice Chancellor for Human Health Sciences […]

Cardiovascular Therapies: Spotlight on Stem Cell Research – W. Douglas Boyd

“Cardiac Tissue Regeneration and Biosurgery” On March 10, 2011, W. Douglas Boyd, M.D., spoke about his work towards developing stem cell-based technologies to repair heart tissue damaged by cardiovascular disease. Boyd is a professor of surgery and director of robotics and biosurgery for the UC Davis Health System. Boyd was introduced by Claire Pomeroy, M.D., […]

Cardiovascular Therapies: Spotlight on Stem Cell Research – Yung-Wei Chi

“Stem Cell Research: Where are we with Peripheral Arterial Disease (PAD)” On March 10, 2011, Yung-Wei Chi, D.O., spoke about a recently launched clinical trial that using a patient’s own stem cells to help prevent amputations due to peripheral arterial disease. Chi is an associate professor of medicine at the UC Davis Vascular Center. Chi […]

Cardiovascular Therapies: Spotlight on Stem Cell Research – Jeanette Owens

“Patient Advocate Speaker” On March 10, 2011, Jeanette Owens spoke about living with peripheral arterial disease and about her hopes for stem cell treatments. Owens was introduced by Claire Pomeroy, M.D., M.B.A., vice chancellor for Human Health Sciences at UC Davis and dean of the UC Davis School of Medicine. Pomeroy is also a member […]

Valentine’s Day Stem Cell Wish: Mending Broken Hearts

These embryonic stem cells in a lab dish form beating heart tissue. CIRM grantees are working to develop new therapies for heart disease based on these cells. For more info visit our the CIRM heart failure fact sheet. Beating heart tissue courtesy of The Exploratorium  and the laboratory of Bruce Conklin at the Gladstone Institute […]