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Human ES cell based therapy of heart failure without allogenic immune rejection

  • Post author:
  • Post published:December 10, 2025
  • Post category:

Heart failure is a major and ever-growing health problem affecting an estimated 5.8 million Americans with about half a million new cases every year. There are limited therapeutic options for…

Continue ReadingHuman ES cell based therapy of heart failure without allogenic immune rejection

Heart Repair with Human Tissue Engineered Myocardium

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  • Post published:December 10, 2025
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Heart disease is the number one cause of morbidity and mortality in the US. With an estimated 1.5 million new or recurrent myocardial infarctions, the total economic burden on our…

Continue ReadingHeart Repair with Human Tissue Engineered Myocardium

Identification of Novel Therapeutics for Danon Disease Using an iPS Model of the Disease

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  • Post published:December 10, 2025
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Autophagy is the cells mechanism for breaking down and recycling proteins. Danon disease is an inherited disorder of autophagy. Patients with this disease have major abnormalities in heart and skeletal…

Continue ReadingIdentification of Novel Therapeutics for Danon Disease Using an iPS Model of the Disease

Extracellular Matrix Bioscaffold Augmented with Human Stem Cells for Cardiovascular Repair

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  • Post published:December 10, 2025
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An estimated 16.3 million Americans suffer from coronary heart disease. Every 25 seconds, someone has a coronary event and every minute, someone dies from one. Treatment for coronary heart disease…

Continue ReadingExtracellular Matrix Bioscaffold Augmented with Human Stem Cells for Cardiovascular Repair

Phase I study of IM Injection of VEGF Producing MSC for the Treatment of Critical Limb Ischemia

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  • Post published:December 10, 2025
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Critical limb ischemia (CLI) represents a significant unmet medical need without any approved medical therapies for patients who fail surgical or angioplasty procedures to restore blood flow to the lower…

Continue ReadingPhase I study of IM Injection of VEGF Producing MSC for the Treatment of Critical Limb Ischemia

Preclinical Development and First-In-Human Testing of GRNCM1 in Advanced Heart Failure

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  • Post published:December 10, 2025
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This application seeks to bring to the clinic a new treatment for myocardial disease based on human embryonic stem cell (hESC) derived cardiomyocytes. hESC-cardiomyocytes have the unique potential to address…

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Human Embryonic Stem Cell-Derived Cardiomyocytes for Patients with End Stage Heart Failure

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  • Post published:December 10, 2025
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Patients with end-stage heart failure (ESHF) have a 2-year survival rate of 50% with conventional medical therapy. This dismal survival rate is actually significantly worse than patients with AIDS, liver…

Continue ReadingHuman Embryonic Stem Cell-Derived Cardiomyocytes for Patients with End Stage Heart Failure

Growing Stem Cell Research in California: Todd McDevitt Lab, Gladstone Institutes

  • Post author:cirmadmin
  • Post published:February 24, 2016
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California's Stem Cell Agency (CIRM) has catalyzed the growth of stem cell research by helping recruit scientists to the state. In this video, we feature Dr. Todd McDevitt, a leading biomedical…

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Heart disease: Progress toward stem cell therapies, a live Google Hangout

  • Post author:cirmadmin
  • Post published:December 20, 2013
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Watch this Google Hangout to learn about recent progress in developing stem cell therapies for heart disease. Hear from stem cell clinical trial participant Fred Lesikar, stem cell experts Dr.…

Continue ReadingHeart disease: Progress toward stem cell therapies, a live Google Hangout

Webinar: Stem Cell Clinical Trial for Heart Disease – Lessons Learned | Eduardo Marbán

  • Post author:cirmadmin
  • Post published:May 6, 2013
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Title: Lessons learned from Phase 1 trial of heart-derived stem cells as we move into Phase 2  Speaker: Eduardo Marbán, M.D., Ph.D. Founder and Chairman of Scientific Advisory Board, Capricor,…

Continue ReadingWebinar: Stem Cell Clinical Trial for Heart Disease – Lessons Learned | Eduardo Marbán
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