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Derivation of Inhibitory Nerve Cells from Human Embryonic Stem Cells

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  • Post published:December 18, 2025
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Parkinson’s disease (PD) is caused by degeneration of a specific population of dopamine-producing nerve cells in the brain and is chronic, progressive, and incurable. Loss of dopamine-containing cells results in…

Continue ReadingDerivation of Inhibitory Nerve Cells from Human Embryonic Stem Cells

MGE Enhancers to Select for Interneuron Precursors Produced from Human ES Cells

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  • Post published:December 18, 2025
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There are now viable experimental approaches to elucidate the genetic and molecular mechanisms that underlie severe brain disorders through the generation of stem cells, called iPS cells, from the skin…

Continue ReadingMGE Enhancers to Select for Interneuron Precursors Produced from Human ES Cells

Inhibitory Interneuron Cell Therapy (NRTX-1001) for the Treatment of Drug-resistant Bilateral Temporal Lobe Epilepsy

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  • Post published:December 17, 2025
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Continue ReadingInhibitory Interneuron Cell Therapy (NRTX-1001) for the Treatment of Drug-resistant Bilateral Temporal Lobe Epilepsy

FIH Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy

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  • Post published:December 17, 2025
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The current therapies for drug-resistant epilepsy are only partially effective and have serious drawbacks.   One treatment that can significantly reduce seizure frequency is the removal of the affected part of…

Continue ReadingFIH Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy

Global gene expression profiling of single inhibitory neurons derived from human stem cells

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  • Post published:September 12, 2024
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Continue ReadingGlobal gene expression profiling of single inhibitory neurons derived from human stem cells
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