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Dual targeting of tyrosine kinase and BCL6 signaling for leukemia stem cell eradication

  • Post author:
  • Post published:November 28, 2025
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Leukemia is the most frequent form of cancer in children and teenagers, but is also common in adults. Chemotherapy has vastly improved the outcome of leukemia over the past four…

Continue ReadingDual targeting of tyrosine kinase and BCL6 signaling for leukemia stem cell eradication

Preclinical development of a pan Bcl2 inhibitor for cancer stem cell directed therapy

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  • Post published:November 28, 2025
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Cancer is the leading cause of death for individuals under 85. Relapse and metastatic disease are the leading causes of cancer related mortality. Anti-apoptotic BCL2 family member overexpression has been…

Continue ReadingPreclinical development of a pan Bcl2 inhibitor for cancer stem cell directed therapy

Niche-Focused Research: Discovery & Development of Hematopoietic Regenerative Factors

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  • Post published:November 28, 2025
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Bone marrow and peripheral blood transplantation utilizing blood stem cells can provide curative treatment for patients with cancers and non-cancerous diseases of the blood and immune systems. Such treatments can…

Continue ReadingNiche-Focused Research: Discovery & Development of Hematopoietic Regenerative Factors

The role of neural stem cells in cerebellar development, regeneration and tumorigenesis

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  • Post published:November 28, 2025
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Stem cells have the remarkable ability to renew themselves and to generate multiple different cell types. This allows them to generate normal tissues during development and to repair tissues following…

Continue ReadingThe role of neural stem cells in cerebellar development, regeneration and tumorigenesis

Epigenetics in cancer stem cell initiation and clinical outcome prediction

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  • Post published:November 28, 2025
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Cancer is responsible for approximately 25% of all deaths in the US and other developed countries. For women, breast and lung cancers and for men, cancers of prostate and lung…

Continue ReadingEpigenetics in cancer stem cell initiation and clinical outcome prediction

Combinatorial Chemistry Approaches to Develop LIgands against Leukemia Stem Cells

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  • Post published:November 28, 2025
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Various cells and organs in the human body originate from a small group of primitive cells called stem cells. Human cancer cells were also recently found to arise from a…

Continue ReadingCombinatorial Chemistry Approaches to Develop LIgands against Leukemia Stem Cells

Mechanisms of Hematopoietic stem cell Specification and Self-Renewal

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  • Post published:November 28, 2025
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During an individual’s lifetime, blood-forming cells in the bone marrow called hematopoietic stem cells (HSCs) supply all the red and white blood cells needed to sustain life. These blood stem…

Continue ReadingMechanisms of Hematopoietic stem cell Specification and Self-Renewal

Patient’s Stage IV Cancer Vanishes during CIRM-Funded Clinical Trial

  • Post author:cirmadmin
  • Post published:January 23, 2018
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This video tells the inspiring story of Tom Howing in his own words. Howing took part in Forty Seven, Inc.'sCIRM-funded clinical trial that's testing an innovative treatment for cancer. In the two minute…

Continue ReadingPatient’s Stage IV Cancer Vanishes during CIRM-Funded Clinical Trial

Role of Stem Cells on Cognitive Dysfunction after Cancer Therapy

  • Post author:cirmadmin
  • Post published:February 20, 2015
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You'd think getting a cancer diagnosis and the subsequent chemo and/or radiation therapy is traumatic enough. But many people receiving cancer therapy also suffer from so-called chemobrain, a condition marked…

Continue ReadingRole of Stem Cells on Cognitive Dysfunction after Cancer Therapy

Michael Rothenberg, Stanford – CIRM Stem Cell #SciencePitch

  • Post author:cirmadmin
  • Post published:March 19, 2013
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Continue ReadingMichael Rothenberg, Stanford – CIRM Stem Cell #SciencePitch
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