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hESC as tools to investigate the neural crest origin of Ewing’s sarcoma

  • Post author:
  • Post published:May 20, 2025
  • Post category:

Human embryonic stem cells (hESC) hold great promise as sources of tissue for regenerative medicine and therapeutics. In addition, their utility as tools to study the origins and biology of…

Continue ReadinghESC as tools to investigate the neural crest origin of Ewing’s sarcoma

Derivation and Characterization of Cancer Stem Cells from Human ES Cells

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  • Post published:May 20, 2025
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Cancer is the leading cause of death for people younger than 85 (1). High cancer mortality rates underscore the need for more sensitive diagnostic techniques as well as therapies that…

Continue ReadingDerivation and Characterization of Cancer Stem Cells from Human ES Cells

Stem Cell-Mediated Oncocidal Gene Therapy of Glioblastoma (GBM)

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  • Post published:May 20, 2025
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Brain tumors (BTs) are incurable, whether they start in the brain or spread there from other sites. Despite advances in surgical, radiation, pharmacologic, and gene therapies, survival with a BT…

Continue ReadingStem Cell-Mediated Oncocidal Gene Therapy of Glioblastoma (GBM)

Stem Cell-mediated Therapy for High-grade Glioma: Toward Phase I-II Clinical Trials

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  • Post published:May 20, 2025
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Despite aggressive multimodal therapy and advances in imaging, surgical and radiation techniques, malignant brain tumors (high-grade gliomas) remain incurable, with survival often measured in months. Treatment failure is largely attributable…

Continue ReadingStem Cell-mediated Therapy for High-grade Glioma: Toward Phase I-II Clinical Trials

Development of Therapeutic Antibodies Targeting Human Acute Myeloid Leukemia Stem Cells

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  • Post published:May 20, 2025
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Acute myeloid leukemia (AML) is a cancer of the blood and bone marrow that is rapidly fatal within months if untreated. Even with aggressive treatment, including chemotherapy and bone marrow…

Continue ReadingDevelopment of Therapeutic Antibodies Targeting Human Acute Myeloid Leukemia Stem Cells

Therapeutic Opportunities To Target Tumor Initiating Cells in Solid Tumors

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  • Post published:May 20, 2025
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Cancer is a major cause of human death worldwide. The vast majority of cancer patients suffer from solid tumors whose growth destroys vital organs. We propose to develop novel therapeutic…

Continue ReadingTherapeutic Opportunities To Target Tumor Initiating Cells in Solid Tumors

Development of Highly Active Anti-Leukemia Stem Cell Therapy (HALT)

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  • Post published:May 20, 2025
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Leukemias are cancers of the blood forming cells that afflict both children and adults. Many drugs have been developed to treat leukemias and related diseases. These drugs are often effective…

Continue ReadingDevelopment of Highly Active Anti-Leukemia Stem Cell Therapy (HALT)

Patient’s Stage IV Cancer Vanishes during CIRM-Funded Clinical Trial

  • Post author:cirmadmin
  • Post published:January 23, 2018
  • Post category:

This video tells the inspiring story of Tom Howing in his own words. Howing took part in Forty Seven, Inc.'sCIRM-funded clinical trial that's testing an innovative treatment for cancer. In the two minute…

Continue ReadingPatient’s Stage IV Cancer Vanishes during CIRM-Funded Clinical Trial

Role of Stem Cells on Cognitive Dysfunction after Cancer Therapy

  • Post author:cirmadmin
  • Post published:February 20, 2015
  • Post category:

You'd think getting a cancer diagnosis and the subsequent chemo and/or radiation therapy is traumatic enough. But many people receiving cancer therapy also suffer from so-called chemobrain, a condition marked…

Continue ReadingRole of Stem Cells on Cognitive Dysfunction after Cancer Therapy

Michael Rothenberg, Stanford – CIRM Stem Cell #SciencePitch

  • Post author:cirmadmin
  • Post published:March 19, 2013
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Continue ReadingMichael Rothenberg, Stanford – CIRM Stem Cell #SciencePitch
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