Disease Focus: Blood Cancer

Development of Therapeutic Antibodies Targeting Human Acute Myeloid Leukemia Stem Cells

Acute myeloid leukemia (AML) is a cancer of the blood and bone marrow that is rapidly fatal within months if untreated. Even with aggressive treatment, including chemotherapy and bone marrow transplantation, five-year overall survival rates range between 30-40%. Evidence indicates that not all cells in this cancer are the same, and that there is a […]

Development of Highly Active Anti-Leukemia Stem Cell Therapy (HALT)

Leukemias are cancers of the blood forming cells that afflict both children and adults. Many drugs have been developed to treat leukemias and related diseases. These drugs are often effective when first given, but in many cases of adult leukemia, the disease returns in a form that is not curable, causing disability and eventual death. […]

Stem Cell Therapies for Leukemia: Marching Toward the Clinic

On March 25th, 2014, California’s Stem Cell Agency (CIRM) hosted a live Google Hangout about recent progress in stem cell based treatment strategies for leukemia. Guest experts included CIRM grantees Dr. Catriona Jamieson of UCSD and Ravi Majeti of Stanford University who discussed their CIRM-funded research projects which aim to bring stem cell based therapies […]

Anica Sayoc, City of Hope – CIRM Stem Cell #SciencePitch

Catriona Jamieson, UCSD – CIRM Stem Cell #SciencePitch

Irving Weissman, Stanford – CIRM Stem Cell #SciencePitch

Leukemia: Advancing Stem Cell Therapies – 2011 CIRM Grantee Meeting

Daniel Goff speaks at the 2011 CIRM Grantee Meeting about identifying potential leukemia drugs that could zero-in on and kill the cancer stems cells that are thought to be responsible for relapse after chemotherapy treatment. Goff is a CIRM Scholar and PhD student at UC San Diego.

Spotlight on Basic Research: Irv Weissman

Irv Weissman, Ph.D., spoke at the “Spotlight on Basic Research,” an educational event presented at the CIRM Governing Board meeting on August 20, 2009. Weissman has a CIRM Comprehensive grant to identify cell surface markers on human embryonic stem cells that distinguish differentiated cells from potentially tumorigenic cells. He also has a CIRM Disease Team […]

Spotlight on Leukemia: Welcoming Remarks

Robert Klein, J.D. and David Brenner, M.D., gave the welcoming remarks for the “Spotlight on Leukemia,” an educational event presented at the CIRM Governing Board meeting on June 18, 2009. Klein is Chair of the CIRM Governing Board and President of Klein Financial Corporation. Brenner is vice chancellor for health sciences and dean at the […]

Spolight on Leukemia: Catriona Jamieson, M.D.

Catriona Jamieson, M.D., spoke at the “Spotlight on Leukemia,” an educational event presented at the CIRM Governing Board meeting on June 18, 2009. Jamieson discussed the stem cell-based research that led to a clinical trial for the treatment of myeloid proliferative diseases, which are blood disorders that can lead to acute leukemia. Jamieson is assistant […]