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MEF2C-Directed Neurogenesis From Human Embryonic Stem Cells

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  • Post published:May 20, 2025
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Understanding differentiation of human embryonic stem cells (hESCs) provides insight into early human development and will help directing hESC differentiation for future cell-based therapies of Parkinson’s disease, stroke and other…

Continue ReadingMEF2C-Directed Neurogenesis From Human Embryonic Stem Cells

Constructing a fate map of the human embryo

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  • Post published:May 20, 2025
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The United States government does not fund research involving human embryos or cells that were grown from them after August 9, 2001. In addition, other restrictions have been imposed that…

Continue ReadingConstructing a fate map of the human embryo

The Dangers of Mitochondrial DNA Heteroplasmy in Stem Cells Created by Therapeutic Cloning

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  • Post published:May 20, 2025
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n therapeutic cloning, a patient’s cell is combined (fused) to an enucleated donated egg (oocyte) from an unrelated woman or from another animal. It is hoped that cellular factors in…

Continue ReadingThe Dangers of Mitochondrial DNA Heteroplasmy in Stem Cells Created by Therapeutic Cloning

Using Human Embryonic Stem Cells to Understand and to Develop New Therapies for Alzheimer’s Disease

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  • Post published:May 20, 2025
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Alzheimer’s Disease (AD) is a progressive incurable disease that robs people of their memory and ability to think and reason. It is emotionally, and sometimes financially devastating to families that…

Continue ReadingUsing Human Embryonic Stem Cells to Understand and to Develop New Therapies for Alzheimer’s Disease

Functional Genomic Analysis of Chemically Defined Human Embryonic Stem Cells

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  • Post published:May 20, 2025
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Regenerative medicine holds the promise that tissues can be engineered in vitro and then transplanted into patients to treat debilitating diseases. Human Embryonic Stem Cells differentiate into a wide array…

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Derivation and characterization of human ES cells from FSHD embryos

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  • Post published:May 20, 2025
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Facioscapulohumeral muscular dystrophy (FSHD) is the third most common hereditary muscular dystrophy. It is autosomal dominant, meaning that if one of the parents has the disease, their children have a…

Continue ReadingDerivation and characterization of human ES cells from FSHD embryos

Modeling Parkinson’s Disease Using Human Embryonic Stem Cells

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  • Post published:May 20, 2025
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Parkinson’s disease (PD) is the most frequent neurodegenerative movement disorder caused by damage of dopamine-producing nerve cells (DA neuron) in patient brain. The main symptoms of PD are age-dependent tremors…

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Development of human ES cell lines as a model system for Alzheimer disease drug discovery

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  • Post published:May 20, 2025
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Alzheimer disease (AD) is a progressive neurodegenerative disorder that currently affects over 4.5 million Americans. By the middle of the century, the prevalence of AD in the USA is projected…

Continue ReadingDevelopment of human ES cell lines as a model system for Alzheimer disease drug discovery

The function of YAP in human embryonic stem cells

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  • Post published:May 20, 2025
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Embryonic stem cells have the potential to generate all tissue types that could be used for regenerative medicine, such as replacement of damaged neurons, replenish of insulin secreting beta cells,…

Continue ReadingThe function of YAP in human embryonic stem cells

Embryonic-Derived Neural Stem Cells for Treatment of Motor Sequelae following Sub-cortical Stroke

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  • Post published:May 20, 2025
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A stroke kills brain cells by interrupting blood flow. The most common “ischemic stroke” is due to blockage in blood flow from a clot or narrowing in an artery. Brain…

Continue ReadingEmbryonic-Derived Neural Stem Cells for Treatment of Motor Sequelae following Sub-cortical Stroke
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