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Non-invasive live imaging of stem cell signature metabolic states

  • Post author:
  • Post published:June 16, 2025
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Stem cells in tissues exhibit unique metabolic states that could distinguish them from other more specialized cells. Using a new type of microscopy we can image the metabolic states of…

Continue ReadingNon-invasive live imaging of stem cell signature metabolic states

Directed Differentiation of Specialized Endothelial Cells

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  • Post published:June 16, 2025
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Vascular endothelial cells (EC) or endothelial progenitor cells (EPC) derived from stem cells could potentially lead to a variety of clinically relevant therapeutic applications, including various strategies for treating heart…

Continue ReadingDirected Differentiation of Specialized Endothelial Cells

Engineered matrices for control of lineage commitment in human pancreatic stem cells

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  • Post published:June 16, 2025
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Patients with end-stage type 1 diabetes (T1D) can be effectively managed by allogeneic islet transplantation. However, a severe cadaveric organ shortage greatly limits use of this promising procedure. Stem cells…

Continue ReadingEngineered matrices for control of lineage commitment in human pancreatic stem cells

Role of intracytoplasmic pattern recognition receptors in HSC engraftment

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  • Post published:June 16, 2025
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The research performed through this project is very important for the fields of solid organ and bone marrow transplantation because it focuses on a potential new target to increase engraftment…

Continue ReadingRole of intracytoplasmic pattern recognition receptors in HSC engraftment

Assessing the mechanism by which the Bone Morphogenetic Proteins direct stem cell fate

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  • Post published:June 16, 2025
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Our goal is to use the mechanisms that generate neuronal networks to create neurons from stem cells, to either replace diseased and damaged tissue or as a source of material…

Continue ReadingAssessing the mechanism by which the Bone Morphogenetic Proteins direct stem cell fate

Innate Immune Regulation of Lung Alveolar Stem Cell Renewal in Mouse and Man

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  • Post published:June 16, 2025
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The lung, along with the skin and gut are the three organs in perpetual contact with our environment. The lung has evolved mechanisms for repairing injury due to exogenous noxious…

Continue ReadingInnate Immune Regulation of Lung Alveolar Stem Cell Renewal in Mouse and Man

New Regulators of Spermatogonial Stem Cells: RHOX Homeobox Transcription Factors

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  • Post published:June 16, 2025
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Infertility afflicts a remarkably high percentage (~15%) of couples, with male factor defects being responsible for more than ½ of these cases. One-third of these male infertility cases have no…

Continue ReadingNew Regulators of Spermatogonial Stem Cells: RHOX Homeobox Transcription Factors

Differentiation of Human Hematopoietic Stem Cells into iNKT Cells

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  • Post published:June 16, 2025
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Blood stem cells living in the bone marrow of adult humans give rise to all of the cells in our blood, including the red blood cells that carry oxygen to…

Continue ReadingDifferentiation of Human Hematopoietic Stem Cells into iNKT Cells
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