Active Awards Portfolio Dashboard

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.


Disease Cell Type Therapeutic or Technology Institution Stage Project Objective Details
Autism, Neurological Disorders iPS Cell Bioinformatics/Computational Tools, Cell Line Generation-Resource, Exploring disease mechanisms, Model system development, Technology UCSD
Research Insights
Developmental Disorders, Intellectual Disability, Neurological Disorders, Pediatrics iPS Cell Exploring disease mechanisms, Exploring stem cell mechanisms, Exploring therapeutic Mechanism, Technology UCSF
Research Insights
Autism, Intellectual Disability, Neurological Disorders iPS Cell Exploring disease mechanisms, Technology, Therapeutic target discovery UCLA
Proof of Concept, Research Insights
Neurological Disorders, Other iPS Cell Cell Line Generation-Resource, Exploring disease mechanisms, Gene editing tools, Specific Cell Type Derivation, Technology UCSF
Research Insights, Tool/Resources/Bottleneck
Autism, Neurological Disorders iPS Cell Bioinformatics/Computational Tools, Exploring disease mechanisms, Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Technology, Therapeutic Approach, Therapeutic target discovery Calibr
Research Insights
Autism, Intellectual Disability, Neurological Disorders iPS Cell Exploring disease mechanisms, Technology Calibr
Research Insights
Autism, Neurological Disorders iPS Cell Exploring disease mechanisms, Model system development, Technology UCSF
Research Insights
Brain Cancer, Cancer, Solid Tumors Cancer Stem Cell Biologic, Gene modification, Therapeutic Approach UC Irvine
Development Candidate, Proof of Concept
Age-related macular degeneration, Retinitis Pigmentosa, Vision Loss Directly Reprogrammed Cell Donor cell therapy, Specific Cell Type Derivation, Technology, Therapeutic Approach CHLA
Development Candidate, Proof of Concept
Amyotrophic Lateral Sclerosis, Neurological Disorders iPS Cell Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach UCSF
Development Candidate
HIV/AIDS, Infectious Disease Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach UCLA
Development Candidate
Neurological Disorders, Neuropathy iPS Cell Small molecule therapy, Therapeutic Approach UCSF
Development Candidate
Brain Cancer, Cancer, Solid Tumors Adult or Tissue Stem Cell Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach COH
Development Candidate
Heart Disease, Heart failure Embryonic Stem Cell, iPS Cell Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach UCSD
Development Candidate
Diabetes, Metabolic Disorders, Type 1 diabetes Adult or Tissue Stem Cell Antibody, Biologic, Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach UCSF
Development Candidate
Neurological Disorders, Traumatic Brain Injury iPS Cell Donor cell therapy, Therapeutic Approach PAVIR
Development Candidate, Proof of Concept
Neurological Disorders, Stroke iPS Cell Donor cell therapy, Therapeutic Approach PAVIR
Development Candidate, Proof of Concept
Neurological Disorders iPS Cell Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach Savanna Bio
Development Candidate, Proof of Concept
Intestinal Disease, Metabolic Disorders iPS Cell Small molecule therapy, Therapeutic Approach UCSF
Development Candidate, Proof of Concept
Amyotrophic Lateral Sclerosis, Neurological Disorders iPS Cell Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach USC
Development Candidate, Proof of Concept
Amyotrophic Lateral Sclerosis, Neurological Disorders iPS Cell Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach Cedars-Sinai
Development Candidate, Proof of Concept
Neurological Disorders iPS Cell Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach UC Davis
Development Candidate, Proof of Concept
Vision Loss Somatic Cell Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach Adverum Biotechnologies Inc.
Development Candidate, Proof of Concept
Blood Cancer, Cancer, Leukemia, Acute Myeloid (AML) Somatic Cell Gene Therapy (All), Gene-modified, donor cell therapy, Immune tolerance/management, Technology, Therapeutic Approach Stanford
Development Candidate
Infectious Disease, Neurological Disorders iPS Cell Gene editing tools, Gene Therapy (All), Gene-modified, donor cell therapy, Immune tolerance/management, Technology, Therapeutic Approach UCSF
Development Candidate, Proof of Concept
Breast Cancer, Cancer, Solid Tumors Cancer Stem Cell Small molecule therapy, Therapeutic Approach Stanford
Development Candidate
Heart Disease Adult or Tissue Stem Cell Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach Cedars-Sinai
Development Candidate, Proof of Concept
Liver Disease, Metabolic Disorders Embryonic Stem Cell Donor cell therapy, Therapeutic Approach USC
Development Candidate, Proof of Concept
Cancer, Prostate Cancer, Solid Tumors iPS Cell Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach UC Irvine
Development Candidate, Proof of Concept
Neurological Disorders, Spinal Cord Injury Embryonic Stem Cell, iPS Cell Donor cell therapy, Therapeutic Approach Gladstone
Development Candidate, Proof of Concept
Cancer, Melanoma, Solid Tumors Adult or Tissue Stem Cell Biologic, Small molecule therapy, Therapeutic Approach, Vaccine UCLA
Development Candidate, Proof of Concept
Breast Cancer, Cancer, Solid Tumors Adult or Tissue Stem Cell, Cancer Stem Cell Small molecule therapy, Therapeutic Approach UCLA
Development Candidate, Proof of Concept
Blood Disorders, Severe Combined Immunodeficiency, Artemis deficient (ART-SCID) Adult or Tissue Stem Cell Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach UC Berkeley
Development Candidate
Duchenne Muscular Dystrophy, Skeletal/Smooth Muscle disorders Other, Somatic Cell Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach UC Davis
Proof of Concept
Lung Disease, Fibrosis, Respiratory Disorders Adult or Tissue Stem Cell Small molecule therapy, Therapeutic Approach Rubedo Life Sciences Inc.
Development Candidate, Proof of Concept
Autism, Intellectual Disability, Metabolic Disorders, Neurological Disorders iPS Cell Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach UCLA
Development Candidate, Proof of Concept
Brain Cancer, Cancer, Solid Tumors Cancer Stem Cell Small molecule therapy, Therapeutic Approach UCLA
Development Candidate, Proof of Concept
Bone or Cartilage Disease, Tendon/Ligament/Connective Tissue Injury or Disorder Embryonic Stem Cell Donor cell therapy, Other Components, Therapeutic Approach Scripps Health
Development Candidate, Proof of Concept
Bone or Cartilage Disease, Intervertebral disc degeneration iPS Cell Donor cell therapy, Other Components, Therapeutic Approach Cedars-Sinai
Development Candidate, Proof of Concept
Metabolic Disorders, Neurological Disorders, Sanfilippo Syndrome/MPS III Embryonic Stem Cell Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach Lundquist Institute
Development Candidate, Proof of Concept
Heart Disease, Heart failure iPS Cell Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach UC Berkeley
Development Candidate, Proof of Concept
Neurological Disorders, Spinal Cord Injury Embryonic Stem Cell, iPS Cell Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach BrainXell Therapeutics, Inc.
Development Candidate, Proof of Concept
Adult or Tissue Stem Cell Cell processing & handling, Gene editing tools, Technology CellFE Biotech Tool/Resources/Bottleneck
Cancer, Solid Tumors Adult or Tissue Stem Cell Technology Stanford Tool/Resources/Bottleneck
iPS Cell Cell processing & handling, Technology Defined Biosciences Tool/Resources/Bottleneck
iPS Cell Cell Line Generation-Resource, Gene Therapy (All), Gene-modified, donor cell therapy, Immune tolerance/management, Technology, Therapeutic Approach HEALIOS NA, Inc. Tool/Resources/Bottleneck
aa Multiple Diseases (Centers & Resoures) Cell processing & handling, Technology UC Davis
Tool/Resources/Bottleneck
Other, Toxicity iPS Cell Model system development, Technology Greenstone Biosciences
Tool/Resources/Bottleneck
Heart Disease iPS Cell Model system development, Technology Organos, Inc.
Tool/Resources/Bottleneck
Kidney Disease, Kidney Failure Adult or Tissue Stem Cell Device, Technology, Therapeutic Approach, Tissue engineering UC Davis
Pre-IND/IDE or Equivalent
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