Active Awards Portfolio Dashboard
It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.
| Disease | Cell Type | Therapeutic or Technology | Institution | Stage | Project Objective | Details |
|---|---|---|---|---|---|---|
| Heart Disease, Heart failure | Antibody, Biologic, Therapeutic Approach | UCLA |  |
IND | ||
| Cancer, Sarcoma, Solid Tumors | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | CHLA | |
IND | |
| Blood Cancer, Cancer, Multiple Myeloma | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCSF | |
IND | |
| Developmental Disorders, Genetic Disorder, Neurological Disorders, Pediatrics | Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach | Elpida Therapeutics | |
IND | ||
| Heart Disease, Heart failure | Adult or Tissue Stem Cell, Somatic Cell | Biologic, Exosomes based therapy, Therapeutic Approach | Cedars-Sinai | |
IND | |
| Cancer, Ovarian Cancer, Solid Tumors | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | COH | |
IND | |
| Epilepsy, Intellectual Disability, Neurological Disorders | Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach | Mahzi Therapeutics | |
IND | ||
| Cystic Fibrosis, Respiratory Disorders | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | Stanford | |
IND | |
| Blood Disorders, Sickle Cell Disease | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UC Davis | |
IND | |
| Age-related macular degeneration, Vision Loss | Embryonic Stem Cell | Biologic, Therapeutic Approach | USC | |
IND | |
| Bone or Cartilage Disease, Cartilage defect | Somatic Cell | Donor cell therapy, Therapeutic Approach | UC Irvine | |
IND | |
| Blood Cancer, Cancer, Leukemia, Acute Myeloid (AML) | Small molecule therapy, Therapeutic Approach | Aspera Biomedicines, Inc. | |
IND | ||
| Age-related macular degeneration, Vision Loss | iPS Cell | Personalized cell therapy, Therapeutic Approach | UCLA | |
IND | |
| Genetic Disorder, Metabolic Disorders | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | Rampart Bioscience | |
IND | |
| Breast Cancer, Cancer, Melanoma, Solid Tumors | Somatic Cell | Donor cell therapy, Therapeutic Approach | Calidi Biotherapeutics, Inc. | |
IND | |
| Immune Disease | Adult or Tissue Stem Cell | Donor cell therapy, Therapeutic Approach | Ossium Health, Inc. | |
IND | |
| Neurological Disorders | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Personalized cell therapy, Therapeutic Approach | UC Davis | |
IND | |
| Genetic Disorder, Metabolic Disorders, Neurological Disorders, Pediatrics | Somatic Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | Stanford | |
IND | |
| Blood Cancer, Cancer, Leukemia, Acute Myeloid (AML) | Cancer Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCSF | |
IND | |
| Blood Disorders, X-linked Chronic Granulomatous Disease | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | ImmunoVec | |
Clinical Trial, Phase 1 or Phase 1/2 | |
| Skin Disease, Wounds, ulcers | Small molecule therapy, Therapeutic Approach | UCLA | |
IND | ||
| Bone or Cartilage Disease, Cartilage defect | Embryonic Stem Cell | Donor cell therapy, Therapeutic Approach | USC | |
IND | |
| Huntington's Disease, Neurological Disorders | Embryonic Stem Cell | Donor cell therapy, Therapeutic Approach | UC Irvine | |
IND | |
| Autism, Neurological Disorders | iPS Cell | Bioinformatics/Computational Tools, Cell Line Generation-Resource, Exploring disease mechanisms, Model system development, Technology | UCSD |  |
Research Insights | |
| Autism, Intellectual Disability, Neurological Disorders | iPS Cell | Exploring disease mechanisms, Technology, Therapeutic target discovery | UCLA | |
Proof of Concept, Research Insights | |
| Developmental Disorders, Intellectual Disability, Neurological Disorders, Pediatrics | iPS Cell | Exploring disease mechanisms, Exploring stem cell mechanisms, Exploring therapeutic Mechanism, Technology | UCSF | |
Research Insights | |
| Autism, Neurological Disorders | iPS Cell | Bioinformatics/Computational Tools, Exploring disease mechanisms, Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Technology, Therapeutic Approach, Therapeutic target discovery | Scripps Research | |
Research Insights | |
| Neurological Disorders, Other | iPS Cell | Cell Line Generation-Resource, Exploring disease mechanisms, Gene editing tools, Specific Cell Type Derivation, Technology | UCSF | |
Research Insights, Tool/Resources/Bottleneck | |
| Autism, Neurological Disorders | iPS Cell | Exploring disease mechanisms, Model system development, Technology | UCSF | |
Research Insights | |
| Autism, Intellectual Disability, Neurological Disorders | iPS Cell | Exploring disease mechanisms, Technology | Scripps Research | |
Research Insights | |
| Dementia, Neurological Disorders, Parkinson's Disease | iPS Cell | Exploring disease mechanisms, Technology | Gladstone | |
Research Insights | |
| Heart Disease, Hypertension, pulmonary arterial, Pulmonary Hypertension | iPS Cell | Exploring disease mechanisms, Technology | Stanford | |
Research Insights, Tool/Resources/Bottleneck | |
| Duchenne Muscular Dystrophy, Muscular Dystrophy, Skeletal/Smooth Muscle disorders | Adult or Tissue Stem Cell | Exploring therapeutic Mechanism, Technology | UCLA | |
Research Insights | |
| Infectious Disease, Neurological Disorders | iPS Cell | Bioinformatics/Computational Tools, Exploring disease mechanisms, Technology | UCSF | |
Research Insights | |
| Diabetes, Metabolic Disorders, Type 1 diabetes | Embryonic Stem Cell, iPS Cell | Immune tolerance/management, Technology | Minutia, Inc. | |
Research Insights | |
| Blood Cancer, Cancer, Leukemia, Acute Myeloid (AML) | Cancer Stem Cell | Exploring disease mechanisms, Technology | Sanford-Burnham | |
Research Insights | |
| Skeletal/Smooth Muscle disorders | Adult or Tissue Stem Cell | UCSD | |
Research Insights | ||
| Infectious Disease, Neurological Disorders, Zika virus | Embryonic Stem Cell, iPS Cell | Exploring disease mechanisms, Technology | UCLA | |
Research Insights | |
| Developmental Disorders, Genetic Disorder, Neurological Disorders, Pediatrics | iPS Cell | Cedars-Sinai | |
Research Insights | ||
| Aging | Adult or Tissue Stem Cell, iPS Cell | Exploring stem cell mechanisms, Specific Cell Type Derivation, Technology | COH | |
Research Insights | |
| Intestinal Disease, Metabolic Disorders, Neurological Disorders, Other | iPS Cell | Personalized cell therapy, Therapeutic Approach | UCSF | |
Proof of Concept, Research Insights | |
| Developmental Disorders, Genetic Disorder, Respiratory Disorders | iPS Cell | Exploring disease mechanisms, Exploring stem cell mechanisms, Model system development, Technology | Lundquist Institute | |
Research Insights | |
| Neurological Disorders | Embryonic Stem Cell | Bioinformatics/Computational Tools, Exploring stem cell mechanisms, Model system development, Technology, Tissue engineering | UCSC | |
Research Insights, Tool/Resources/Bottleneck | |
| Developmental Disorders, Genetic Disorder, Intellectual Disability, Neurological Disorders, Rett's Syndrome | iPS Cell | Exploring disease mechanisms, Technology | UCLA | |
Research Insights | |
| Lung Disease, Fibrosis, Respiratory Disorders | Adult or Tissue Stem Cell | Exploring disease mechanisms, Exploring stem cell mechanisms, Technology, Therapeutic target discovery | UCSF | |
Research Insights | |
| Fertility | Embryonic Stem Cell, iPS Cell | Model system development, Technology | UCLA | |
Research Insights, Tool/Resources/Bottleneck | |
| Retinitis Pigmentosa, Vision Loss | iPS Cell | Exploring disease mechanisms, Technology | UCSF | |
Research Insights, Tool/Resources/Bottleneck | |
| Cystic Fibrosis, Respiratory Disorders | Adult or Tissue Stem Cell | Cell delivery or targeting, Gene editing tools, Technology | UCLA | |
Research Insights, Tool/Resources/Bottleneck | |
| Amyotrophic Lateral Sclerosis, Neurological Disorders | iPS Cell | Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach | UC Irvine | |
Proof of Concept, Research Insights | |
| Neurological Disorders | Adult or Tissue Stem Cell, iPS Cell | Exploring stem cell mechanisms, Specific Cell Type Derivation, Technology | UCSF | |
Research Insights |
