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CIRM’s Blog: The Stem Cellar

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  • Experimental treatment brings relief for a dancer with chronic knee pain July 24, 2026
    From the age of three, Tara Radcliffe Ghiglieri danced almost every day, leaping, pirouetting, tapping, and high kicking her way into a Broadway career that included a multi-year stint as a Radio City Rockette. She trained hard, at times rehearsing eight hours a day, six days a week. “And performance days could be up to […]
  • Early trial shows promise for one‑shot cure for HIV  July 14, 2026
    By Holly Alyssa MacCormick  A single infusion of a modified CAR-T cell therapy could pave the way for a potential one-shot cure for HIV, according to preliminary findings of a small, early-stage clinical trial. Steven G. Deeks, MD, the principal investigator of this California Institute for Regenerative Medicine (CIRM)-funded clinical trial, discussed the findings at a recent CIRM board meeting.  Roughly 40 million people worldwide and more than 143,000 Californians have HIV. Currently, HIV is treated […]
  • Genascence discusses gene therapy for knee osteoarthritis July 1, 2026
    Knee joint pain rarely gets counted among major public‑health burdens. Yet it affects more than 3 million Californians and 34 million people across the U.S., with both massive economic and health consequences. Costly Impact In California alone, the cost of knee replacement surgeries exceeds $8 billion annually, according to Thomas Chalberg, PhD, founder and CEO […]

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