Dissecting the cellular and molecular interactions between embryo and endometrium during human implantation.
Grant Award Details
Grant Type:
Grant Number:
DISC0-17685
Investigator(s):
Award Value:
$2,290,157
Status:
Pre-Active
Grant Application Details
Application Title:
Dissecting the cellular and molecular interactions between embryo and endometrium during human implantation.
Public Abstract:
Research Objective
This research will define the dynamic mechanisms of human embryo implantation by integrating live imaging, spatial multi-omics, and gene editing in physiologically relevant stem cell-based models.
Impact
This research will uncover factors driving embryo implantation and early pregnancy, address IVF implantation failure, and inform development of targeted therapies to improve fertility outcomes.
This research will define the dynamic mechanisms of human embryo implantation by integrating live imaging, spatial multi-omics, and gene editing in physiologically relevant stem cell-based models.
Impact
This research will uncover factors driving embryo implantation and early pregnancy, address IVF implantation failure, and inform development of targeted therapies to improve fertility outcomes.