Development of in vitro and in vivo functional human synthetic kidney organoid (hSKO) model as a platform technology for kidney research
Grant Award Details
Grant Type:
Grant Number:
DISC0-17626
Investigator(s):
Award Value:
$2,287,926
Status:
Pre-Active
Grant Application Details
Application Title:
Development of in vitro and in vivo functional human synthetic kidney organoid (hSKO) model as a platform technology for kidney research
Public Abstract:
Research Objective
Development of a human stem cell-derived, spatially-patterned, mature and functional human synthetic kidney organoid (hSKO) model as a platform technology for basic and translational kidney research.
Impact
Lack of a reliable human kidney model is a major bottleneck in kidney research. This project will establish the most physiologically relevant model for studying human kidney development and disease.
Development of a human stem cell-derived, spatially-patterned, mature and functional human synthetic kidney organoid (hSKO) model as a platform technology for basic and translational kidney research.
Impact
Lack of a reliable human kidney model is a major bottleneck in kidney research. This project will establish the most physiologically relevant model for studying human kidney development and disease.
