Developing replacement islet cells for diabetes using human stem cells
Grant Award Details
Grant Type:
Grant Number:
DISC0-17421
Investigator(s):
Award Value:
$3,943,364
Status:
Pre-Active
Grant Application Details
Application Title:
Developing replacement islet cells for diabetes using human stem cells
Public Abstract:
Research Objective
We will identify genetic regulators and intercellular signals that promote islet cell function, and apply our work to advance stem cell biology for generating replacement islets to reverse diabetes.
Impact
Our efforts could generate improved, safer replacement islet cells for type 1 diabetes, and islets matured in vitro to model type 1 or 2 diabetes pathogenesis, and develop personalized therapeutics.
We will identify genetic regulators and intercellular signals that promote islet cell function, and apply our work to advance stem cell biology for generating replacement islets to reverse diabetes.
Impact
Our efforts could generate improved, safer replacement islet cells for type 1 diabetes, and islets matured in vitro to model type 1 or 2 diabetes pathogenesis, and develop personalized therapeutics.
