Allele Prospector: Leveraging human genetic variation to enable therapeutic genome editing in hundreds of disease genes
Grant Award Details
Grant Type:
Grant Number:
DISC0-17363
Investigator(s):
Award Value:
$5,112,209
Status:
Pre-Active
Grant Application Details
Application Title:
Allele Prospector: Leveraging human genetic variation to enable therapeutic genome editing in hundreds of disease genes
Public Abstract:
Research Objective
We are building a foundational platform for developing genome editing technologies that increase patient coverage by 20-40X and can be applied to over 700 genetic diseases in diverse populations.
Impact
Many genetic diseases have hundreds of different mutations so correcting mutations one-by-one is impractical. We are developing an approach that can reach more patients with curative treatments.
We are building a foundational platform for developing genome editing technologies that increase patient coverage by 20-40X and can be applied to over 700 genetic diseases in diverse populations.
Impact
Many genetic diseases have hundreds of different mutations so correcting mutations one-by-one is impractical. We are developing an approach that can reach more patients with curative treatments.
