Generation of human universal donor iPS cells

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• Post published:April 19, 2026
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Translational Candidate Universal donor cell that is a genetically-engineered iPSC clone and is equipped with a safety switch. Area of Impact Regenerative medicine including replacement therapies affected by immune rejection…

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Living Synthetic Vascular Grafts with Renewable Endothelium

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• Post published:April 19, 2026
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Translational Candidate LXW7 coated ePTFE vascular graft achieves rapid endothelization and improved graft patency by capturing endogenous endothelial progenitor cells Area of Impact This technology will produce long-lasting vascular grafts…

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A targeted antisense oligonucleotide therapeutic strategy for Timothy syndrome

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• Post published:April 19, 2026
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GlyTR2 CAR T cell translation: safe pan-cancer killing via velcro-like density-dependent targeting of cancer glycans

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FM-IL2 CAR T cells for Pancreatic Cancer

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Lep001 – gene therapy for the treatment of congenital lipodystrophy

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• Post published:April 19, 2026
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Development of an off-the-shelf iPSC derived CAR T cell therapy for the treatment of solid tumors

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Development of an AAV Epigenetic Gene Therapy for Gain-of-Function SCN9A Disorders and Chronic Pain

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Evaluation of an ex vivo lentiviral gene therapy for the treatment of Angelman syndrome

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Genetic Therapy Targeting mHTT mRNA and Somatic Expansion to Treat Huntington’s Disease

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