Research Objective We provide mechanistic insight into idiopathic Intellectual Disability (ID) and Autism Spectrum Disorder (ASD) based on aberrant redox-mediated posttranslational modifications related to air pollution Impact How air pollution…
Research Objective We will uncover pathways through which ASD mutations cause disease and close the gap from disease research to therapeutic testing using organoids, primary human neurons, machine learning and…
The goal of this project is to support the discovery and evaluation of novel therapeutics using stem cell-based models and drug and CRISPR screening. The facility will provide California researchers…
This proposal will create a laboratory that will provide training in advanced stem cell modeling technology, particularly organ chip technology. This laboratory aims to train stem cell researchers in using…
We propose to expand and enhance our stem cell core, a key resource for the local area.This project will accelerate new therapies and train stem cell scientists. We propose to…
The proposed CIRM ASCEND Center provides cutting-edge organoid-based services, offering consultation, optimized protocols, and genomic analysis. We also offer comprehensive training, workshops, and access to data, empowering researchers across California…
This project enhances stem cell access, scalability, and collaboration. It offers characterized hPSC lines, CRISPR editing, and differentiation on automated platforms accelerating progress in biology, disease research, and regenerative medicine.…
Our broad objective is to expand access to equipment, services, and training within our areas of excellence. Through knowledge sharing and collaboration, we aim to add value to the CIRM…
The Cal Poly Humboldt Shared Resource Laboratory for Human Stem Cell-Based Modeling (SRL-hSC) will provide modeling resources and educational offerings to researchers, educators, and students in our rural and remote…
The areas of focus for our SRL will include induced pluripotent stem cell generation and characterization, cell differentiation and generation of a microvascular tissue model and in vivo models. Our…
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