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Role of Innate Immunity in hematopoeitic stem cell-mediated allograft tolerance

  • Post author:
  • Post published:May 24, 2025
  • Post category:

The research proposed in this project has very high potential to identify new medications to boost the natural ability of stem cells to prevent rejection of transplanted organs. This is…

Continue ReadingRole of Innate Immunity in hematopoeitic stem cell-mediated allograft tolerance

Engineered immune tolerance by Stem Cell-derived thymic regeneration

  • Post author:
  • Post published:May 24, 2025
  • Post category:

Stem cell therapies have the potential to transform medicine by allowing the regeneration of tissues or organs damaged by disease or trauma. In order for stem cell therapies to proceed,…

Continue ReadingEngineered immune tolerance by Stem Cell-derived thymic regeneration

Inactivating NK cell reactivity to facilitate transplantation of stem cell derived tissue

  • Post author:
  • Post published:May 24, 2025
  • Post category:

One of the great promises of stem cell research is that it will one day be possible to prepare replacement cells or organs from stem cells such as embryonic stem…

Continue ReadingInactivating NK cell reactivity to facilitate transplantation of stem cell derived tissue

Regulatory T cell induced tolerance to ESC transplantation

  • Post author:
  • Post published:May 24, 2025
  • Post category:

The goals of this proposal are to utilize cell populations known to control immune reactions termed regulatory T cells and study their ability to protect embryonic stem cells (ESC) from…

Continue ReadingRegulatory T cell induced tolerance to ESC transplantation

Induction of immune tolerance after spinal grafting of human ES-derived neural precursors

  • Post author:
  • Post published:May 24, 2025
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Previous clinical studies have shown that grafting of human fetal brain tissue into the CNS of adult recipients can be associated with long-term (more then 10 years) graft survival even…

Continue ReadingInduction of immune tolerance after spinal grafting of human ES-derived neural precursors

Role of HLA in neural stem cell rejection using humanized mice

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  • Post published:May 24, 2025
  • Post category:

One of the key issues in stem cell transplant biology is solving the problem of transplant rejection. Despite over three decades of research in human embryonic stem cells, little is…

Continue ReadingRole of HLA in neural stem cell rejection using humanized mice

Role of HLA in neural stem cell rejection using humanized mice

  • Post author:
  • Post published:May 24, 2025
  • Post category:

One of the key issues in stem cell transplant biology is solving the problem of transplant rejection. Despite over three decades of research in human embryonic stem cells, little is…

Continue ReadingRole of HLA in neural stem cell rejection using humanized mice

Engineering Embryonic Stem Cell Allografts for Operational Tolerance

  • Post author:
  • Post published:May 24, 2025
  • Post category:

Stem cells, like all transplants not derived from an identical twin, are subject to scrutiny by the immune system and, without medical interventions that suppress the immune system, are usually…

Continue ReadingEngineering Embryonic Stem Cell Allografts for Operational Tolerance

Induction of immune tolerance to human embryonic stem cell-derived allografts

  • Post author:
  • Post published:May 24, 2025
  • Post category:

Human embryonic stem cells (hESCs) can undergo unlimited reproduction and retain the capability to differentiate into all cell types in the body. Therefore, as a renewable source of various cell…

Continue ReadingInduction of immune tolerance to human embryonic stem cell-derived allografts

Engineering Thymic Regeneration to Induce Tolerance

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  • Post published:May 24, 2025
  • Post category:

A healthy immune system produces T cells that can recognize and react against foreign molecules (antigens) to protect against infection, while leaving normal host cells with “self antigens” undamaged. All…

Continue ReadingEngineering Thymic Regeneration to Induce Tolerance
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