Hypo-immunogenic cardiac patches for myocardial regeneration

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• Post published:November 18, 2025
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Research Objective To engineer a cardiac patch to restore function after a heart attack while avoiding an immune response (“hypo-immunogeneic” CP) when transplanted into a genetically distinct (“allogenic”) individual. Impact…

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Developing a personalized approach to beta cell replacement for patients with a genetic form of diabetes

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• Post published:November 18, 2025
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Research Objective To correct a gene mutation in a patient's stem cells and produce functional replacement cells for the patient to cure their diabetes. Impact WE expect that this project…

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Generation of human universal donor iPS cells

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• Post published:November 18, 2025
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Translational Candidate Universal donor cell that is a genetically-engineered iPSC clone and is equipped with a safety switch. Area of Impact Regenerative medicine including replacement therapies affected by immune rejection…

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A targeted antisense oligonucleotide therapeutic strategy for Timothy syndrome

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• Post published:November 18, 2025
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GlyTR2 CAR T cell translation: safe pan-cancer killing via velcro-like density-dependent targeting of cancer glycans

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• Post published:November 18, 2025
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FM-IL2 CAR T cells for Pancreatic Cancer

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• Post published:November 18, 2025
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Lep001 – gene therapy for the treatment of congenital lipodystrophy

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• Post published:November 18, 2025
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Development of an off-the-shelf iPSC derived CAR T cell therapy for the treatment of solid tumors

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• Post published:November 18, 2025
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Development of an AAV Epigenetic Gene Therapy for Gain-of-Function SCN9A Disorders and Chronic Pain

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• Post published:November 18, 2025
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Evaluation of an ex vivo lentiviral gene therapy for the treatment of Angelman syndrome

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• Post published:November 18, 2025
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