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Etsrp/ER71 mediated stem cell differentiation into vascular lineage

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  • Post published:June 6, 2025
  • Post category:

Human embryonic stem cells (hESC) have the potential to differentiate into all of the cell types that make up the body. Therefore, hESCs are promising tools for the treatment of…

Continue ReadingEtsrp/ER71 mediated stem cell differentiation into vascular lineage

Understanding the role of LRRK2 in iPSC cell models of Parkinson’s Disease

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  • Post published:June 6, 2025
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The goal of this research is to utilize novel research tools to investigate the molecular mechanisms that cause Parkinson’s disease (PD). The proposed work builds on previous funding from CIRM…

Continue ReadingUnderstanding the role of LRRK2 in iPSC cell models of Parkinson’s Disease

Identifying sources of mutation in human induced pluripotent stem cells by whole genome sequencing

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  • Post published:June 6, 2025
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Stem cell research offers new tools to help treat and cure diseases that affect diverse cells types in the body such as neurological diseases, heart disease and diabetes by producing…

Continue ReadingIdentifying sources of mutation in human induced pluripotent stem cells by whole genome sequencing

Ubiquitin-dependent control of hESC self-renewal and expansion

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  • Post published:June 6, 2025
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Human embryonic stem cells (hESCs) or induced pluripotent stem cells (iPSCs) provide an invaluable resource for regenerative medicine and disease modeling. To be able to use these cells in the…

Continue ReadingUbiquitin-dependent control of hESC self-renewal and expansion

Forming the Hematopoietic Niche from Human Pluripotent Stem Cells

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  • Post published:June 6, 2025
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The clinical potential of pluripotent stem cells for use in regenerative medicine will be realized only when the process by which tissues are generated from these cells is significantly more…

Continue ReadingForming the Hematopoietic Niche from Human Pluripotent Stem Cells

Biological relevance of microRNAs in hESC differentiation to endocrine pancreas

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  • Post published:June 6, 2025
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There remains an urgent and critical need for a cell-based cure of diabetes, one of the most costly diseases in California. Islet transplantation with persistent immune suppression has shown promise…

Continue ReadingBiological relevance of microRNAs in hESC differentiation to endocrine pancreas

Induced Pluripotent Stem Cells for Tissue Regeneration

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  • Post published:June 6, 2025
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Induced pluripotent stem cells (iPSCs) have tremendous potential for patient-specific cell therapies, which bypasses immune rejection issues and ethical concerns for embryonic stem cells (ESCs). However, to fully harness the…

Continue ReadingInduced Pluripotent Stem Cells for Tissue Regeneration

Niche-Focused Research: Discovery & Development of Hematopoietic Regenerative Factors

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  • Post published:June 6, 2025
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Bone marrow and peripheral blood transplantation utilizing blood stem cells can provide curative treatment for patients with cancers and non-cancerous diseases of the blood and immune systems. Such treatments can…

Continue ReadingNiche-Focused Research: Discovery & Development of Hematopoietic Regenerative Factors

Epithelial progenitors and the stromal niche as therapeutic targets in lung disease

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  • Post published:June 6, 2025
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Chronic lung disease is an enormous societal and medical problem in California and the nation as a whole, representing the third most likely cause of death. Treatment costs were $389.2…

Continue ReadingEpithelial progenitors and the stromal niche as therapeutic targets in lung disease

Repair and regeneration of the nephron

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  • Post published:June 6, 2025
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Kidney function is essential for removing the wastes that result from normal cell function and maintaining water and salt balance in our internal tissues. These actions are carried out by…

Continue ReadingRepair and regeneration of the nephron
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