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A Requirement for Protein Homeostasis in the Mediation of Stem Cell Health

  • Post author:
  • Post published:October 16, 2025
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Experiments with human embryonic stem cells (hESCs) have clearly demonstrated their capacity to replicate continuously and maintain pluripotency. We hypothesize that the health of hESCs depends in part upon an…

Continue ReadingA Requirement for Protein Homeostasis in the Mediation of Stem Cell Health

Misregulated Mitophagy in Parkinsonian Neurodegeneration

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  • Post published:October 16, 2025
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Parkinson’s disease (PD), is one of the leading causes of disabilities and death and afflicting millions of people worldwide. Effective treatments are desperately needed but the underlying molecular and cellular…

Continue ReadingMisregulated Mitophagy in Parkinsonian Neurodegeneration

Induced pluripotent stem cells from children with autism spectrum disorders

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  • Post published:October 16, 2025
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Autism spectrum disorders (ASD) are a family of disabling disorders of the developing brain that affect about 1% of the population. Studying the biology of these conditions has been difficult…

Continue ReadingInduced pluripotent stem cells from children with autism spectrum disorders

Using human induced pluripotent stem cells to improve our understanding of Idiopathic Pulmonary Fibrosis

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  • Post published:October 16, 2025
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Idiopathic Pulmonary Fibrosis (IPF) is a progressive and generally fatal disease that causes scarring of the lungs and therefore an inability to breathe. Its true prevalence is unknown, as it…

Continue ReadingUsing human induced pluripotent stem cells to improve our understanding of Idiopathic Pulmonary Fibrosis

iPSC-derived Hepatocytes as Platforms for Research in Viral Hepatitis and Non-alcoholic Steatohepatitis

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  • Post published:October 16, 2025
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Hepatitis C and fatty liver disease are the two most common liver diseases in California. Individuals from different backgrounds are susceptible to these liver diseases, but they have unique genetic…

Continue ReadingiPSC-derived Hepatocytes as Platforms for Research in Viral Hepatitis and Non-alcoholic Steatohepatitis

In Utero Embryonic Stem Cell Transplantation to Treat Congenital Anomalies

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  • Post published:October 16, 2025
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Many fetuses with congenital blood stem cell disorders such as sickle cell disease or thalassemia are prenatally diagnosed early enough in pregnancy to be treated with stem cell transplantation. The…

Continue ReadingIn Utero Embryonic Stem Cell Transplantation to Treat Congenital Anomalies

Human iPSC modeling and therapeutics for degenerative peripheral nerve disease

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  • Post published:October 16, 2025
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The applicant is an MD/PhD trained physician scientist, whose clinical expertise is neuromuscular disorders including peripheral nerve disease. The proposal is aimed at providing a research proposal and career development…

Continue ReadingHuman iPSC modeling and therapeutics for degenerative peripheral nerve disease

Enhancing hair cell regeneration in mouse and human inner ear

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  • Post published:October 16, 2025
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Hearing loss (HL) is a permanent sensory disorder affecting over 278 million people worldwide. In the US and California, 20% of individuals suffer from this sensory deficit. Those affected range…

Continue ReadingEnhancing hair cell regeneration in mouse and human inner ear

Stem cell therapy for inflammatory bowel disease

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  • Post published:October 16, 2025
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One of the most promising approaches that physicians foresee for treating human disease is regenerative medicine. A major aim in this field is to restore function by repairing damaged organs.…

Continue ReadingStem cell therapy for inflammatory bowel disease

White matter neuroregeneration after chemotherapy: stem cell therapy for “chemobrain”

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  • Post published:October 16, 2025
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Chemotherapy for cancer is often life saving, but it also causes a debilitating syndrome of impaired cognition characterized by deficits in attention, concentration, information processing speed, multitasking and memory. As…

Continue ReadingWhite matter neuroregeneration after chemotherapy: stem cell therapy for “chemobrain”
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