Year 1

The Shared Research Laboratory at the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC has provided support and training for stem cell researchers at USC and neighboring institutions. We have supplied training and expertise for a diverse range of research projects on human embryonic stem cells and induced pluripotent stem cells, including one project that evolved into a successful CIRM Disease Team application in the field of macular degeneration. The services supplied by our facility include quality controlled cell lines and reagents, biobanking, and access to communal research space and specialized equipment.
The SRL also collaborates with scientists in several research projects. We worked with Dr. Pin Wang to develop new methods for genetic manipulation of human embryonic stem cells. We collaborated with Dr. Gregor Adams in developing techniques for hematopoietic differentiation of human ES cells. Finally the SRL participated in the International Stem Cell Initiative studies of media for propagation of human ES cells and human pluripotent stem cell genetic and epigenetic stability.
The SRL is managed by Dr. Victoria Fox with the assistance of four scientific staff.
We operate two formal training courses, one on Human Pluripotent Stem Cell Culture, and the second on RNAi Mediated Gene Knockdown in Human Pluripotent Stem Cells. We have had extensive participation in these courses from USC students and staff and from our partners in the CIRM Bridges to Stem Cell Research Program. The SRL has also served as a training facility for interns in the CIRM Bridges to Stem Cell Research Program.