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A hNSC Development Candidate for Huntington’s Disease

  • Post author:
  • Post published:July 1, 2025
  • Post category:

Huntington’s disease (HD) is a devastating degenerative brain disease with at least a 1 in 10,000 prevalence that inevitably leads to death. These numbers do not fully reflect the large…

Continue ReadingA hNSC Development Candidate for Huntington’s Disease

Pre-clinical development of gene correction therapy of hematopoietic stem cells for SCID-X1

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  • Post published:July 1, 2025
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Severe combined immunodeficiency caused by mutations in the IL2RG gene on the x-chromosome (SCID-X1 or "bubble boy disease") is a devastating genetic disease that results in boys not being able…

Continue ReadingPre-clinical development of gene correction therapy of hematopoietic stem cells for SCID-X1

Placental Stem Cells for the In Utero Treatment of Spina Bifida

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  • Post published:July 1, 2025
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Myelomeningocele – also known as spina bifida – is a devastating and costly defect that causes lifelong paralysis as well as bowel and bladder incontinence in newborns. It is one…

Continue ReadingPlacental Stem Cells for the In Utero Treatment of Spina Bifida

Human Stem-Cell Based Development of a Potent Alzheimer’s Drug Candidate

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  • Post published:July 1, 2025
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Over 6 million people in the US suffer from Alzheimer’s disease (AD). There are no drugs that prevent the death of nerve cells in AD, nor has any drug been…

Continue ReadingHuman Stem-Cell Based Development of a Potent Alzheimer’s Drug Candidate

CIRM Planning Grant in Leukemia

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  • Post published:July 1, 2025
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Leukemias are cancers of the blood forming cells that afflict both children and adults. Many drugs have been developed to treat leukemias and related diseases, but in many cases of…

Continue ReadingCIRM Planning Grant in Leukemia

{REDACTED} Cardiovascular Regenerative Team

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  • Post published:July 1, 2025
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Heart failure affects 5 million patients in the U.S., representing the most common cause of hospital admission and resulting in 300,000 deaths annually. Despite aggressive treatment with advanced pharmacotherapies and…

Continue Reading{REDACTED} Cardiovascular Regenerative Team

“Stem Cell Therapies for Heart Failure”

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  • Post published:July 1, 2025
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Our multi-institutional program is dedicated to the treatment of heart failure, which has become a leading cause of death in California and the U. S. The high death toll continues…

Continue Reading“Stem Cell Therapies for Heart Failure”

Genetically-modified neural stem cells for treatment of high-grade glioma

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  • Post published:July 1, 2025
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Our proposal details assembly of a multidisciplinary Disease Team whose goal will be to take into the clinic a novel and promising stem cell-based strategy for selectively targeting invasive tumor…

Continue ReadingGenetically-modified neural stem cells for treatment of high-grade glioma

{REDACTED} Heart Disease Regenerative Medicine Team Planning Award

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  • Post published:July 1, 2025
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The present planning grant application lays the groundwork for a collaborative heart disease regenerative medicine team. We plan to develop sequential preclinical and clinical investigations directed at regenerative stem cell-based…

Continue Reading{REDACTED} Heart Disease Regenerative Medicine Team Planning Award

Huntington’s Disease Team

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  • Post published:July 1, 2025
  • Post category:

Huntington’s disease (HD) is a devastating degenerative brain disease with a 1 in 10,000 risk of having a mutation that inevitably leads to death. These numbers do not fully reflect…

Continue ReadingHuntington’s Disease Team
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